Combined lung transplantation and percutaneous septal defect closure for end-stage atrial septal defect associated pulmonary arterial hypertension

ConclusionDLT followed by percutaneous ASD closure is an efficient therapeutic approach in patients with end-stage ASD associated PAH that may offer an alternative option to HLT.
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research

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Publication date: Available online 11 February 2020Source: Journal of Veterinary CardiologyAuthor(s): Takeshi Mizuno, Masashi Mizuno, Kayoko Harada, Hiroshi Takano, Asako Shinoda, Arane Takahashi, Kazuya Mamada, Kazuki Takamura, Ayaka Chen, Koji Iwanaga, Shin Ono, Masami UechiAbstractA 5-year-old male Toy Poodle was referred for corrective surgery of an atrial septal defect. A sinus venosus-type atrial septal defect (ASD) with partial anomalous venous connection, suspected pulmonary hypertension and pulmonary edema was confirmed by radiography, echocardiography, and cardiac computed tomography. Thoracic radiographs showed ...
Source: Journal of Veterinary Cardiology - Category: Veterinary Research Source Type: research
AbstractTranscatheter closure of large atrial septal defects (ASDs) remains controversial. The aim of this study was to evaluate the feasibility and safety of transthoracic echocardiography (TTE)-guided transcatheter closure of large ASDs. Patients with large secundum ASDs ( ≥ 30 mm) who underwent device closure were retrospectively reviewed. TTE was performed to guide ASD occluder positioning and assess the immediate and long-term outcomes. A total of 60 patients (median age 43.5 years, range 15–78 years) were enrolled in the study. The median ASD size was 35  mm (range 30–42 ...
Source: Pediatric Cardiology - Category: Cardiology Source Type: research
Conclusionsurgical correction of ASD in adults is safe and efficacious. Cardiac remodelling after ASD closure in the adult is a common and an early event and prevents late morbidity, which is in most cases due to arrhythmias. The mode of closure does not seem to significantly impact remodelling.
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research
Publication date: January 2020Source: Archives of Cardiovascular Diseases Supplements, Volume 12, Issue 1Author(s): M. Drissa, H. Jamila, H. DrissaBackgroundAtrial septal defect (ASD) is one of the most common causes of congenital heart disease manifested in adulthood and a subgroup of patients may not develop symptoms until late adulthood.Aim of studyThe aim of our study was to describe clinical and likelihood picture of adults over 60 years born with an ASD type II.MethodsWe performed a retrospective analysis of adult's ASD referred to our institution from 2010 through 2018. Clinical, electrocardiographic, echocardiograp...
Source: Archives of Cardiovascular Diseases Supplements - Category: Cardiology Source Type: research
Patients with simple shunt lesions, such as atrial septal defect (ASD), ventricular septal defect (VSD) and persistent arterial duct (PDA) remain at risk of developing pulmonary hypertension (PH) even after correction of their cardiac defect. We aimed to assess the contemporary prevalence of PH in a well characterized nationwide group of patients based on the German National Register for Congenital Heart Defects.
Source: International Journal of Cardiology - Category: Cardiology Authors: Source Type: research
A 3-YEAR-OLD-BOY (weight, 12.8 kg; height, 95 cm; body surface area, 0.6 m2) with Noonan syndrome and sickle cell trait was taken to the operating room for correction of a large (20 mm) ostium secundum atrial septal defect and pulmonary artery stenosis. Intraoperative transesophageal echocardiography (TEE) confirmed the diagnosis and also suggested the presence of a left superior vena cava (LSVC) with a normal mitral valve (Fig 1). However, the coronary sinus could not be traced to the right atrium suggesting the possibility of a partially unroofed coronary sinus.
Source: Journal of Cardiothoracic and Vascular Anesthesia - Category: Anesthesiology Authors: Tags: Diagnostic Dilemma Source Type: research
Conclusions: In patients with PAH, exercise training maintains exercise capacity, right ventricular function and daily physical activity up to 6 months after the end of the program.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Pulmonary hypertension Source Type: research
This report is the first instance in which a patient with severe PAH, survived a successful atrial septal defect (ASD) repair and bilateral lung transplantation during puerperium. Patient concerns: A 42-year-old pregnant woman with congenital heart disease (CHD) and severe PAH was admitted to our hospital for the management of pregnancy and delivery. The patient was diagnosed with severe PAH in 2013, and no significant improvements or deteriorations were found until this pregnancy-related hospital admission. Diagnosis: The patient was diagnosed with CHD and severe PAH in 2013 with color Doppler echocardiography, righ...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Conclusion: Other causes need to be excluded carefully before giving a diagnosis of PAH with AOSD. Early diagnosis and aggressive treatments are pivotal to improve the quality of life and the survival of patients.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Gore won the European CE Mark for its GORE CARDIOFORM ASD Occluder, a device designed for percutaneous, transcatheter closure of ostium secundum atrial defects (ASDs). The occluder recently completed a clinical study involving 125 patients with ASD, ...
Source: Medgadget - Category: Medical Devices Authors: Tags: Cardiac Surgery Cardiology Radiology Source Type: blogs
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