Study reveals a new approach to enhancing response to immunotherapy in melanoma

(Sanford Burnham Prebys Medical Discovery Institute) Scientists at Sanford Burnham Prebys have identified a new way to boost the immune system's ability to fight cancer. The study used a mouse model to identify the importance of the Siah2 protein in the control of immune cells called T regulatory cells (Tregs), which limit the effectiveness of currently used immunotherapies. The research, which offers a new avenue to pursue immunotherapy in cases where the treatment fails, was published today in Nature Communications.
Source: EurekAlert! - Biology - Category: Biology Source Type: news