[ASAP] Incorporation of Agouti-Related Protein (AgRP) Human Single Nucleotide Polymorphisms (SNPs) in the AgRP-Derived Macrocyclic Scaffold c[Pro-Arg-Phe-Phe-Asn-Ala-Phe- < sc > d < /sc > Pro] Decreases Melanocortin-4 Receptor Antagonist Potency and Results in the Discovery of Melanocortin-5 Receptor Antagonists

Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.9b00860

Source: Journal of Medicinal Chemistry - January 6, 2020 Category: Chemistry Authors: Zoe M. Koerperich †, Mark D. Ericson†, Katie T. Freeman†, Robert C. Speth‡§, Irina D. Pogozheva?, Henry I. Mosberg?, and Carrie Haskell-Luevano*† Source Type: research