Phase I dose-escalation study of the safety, tolerability, and pharmacokinetics of aflibercept in combination with S-1 in Japanese patients with advanced solid malignancies

Conclusions The tolerability and safety of aflibercept 2  mg/kg in combination with S-1 was confirmed in Japanese patients with advanced solid tumors.
Source: Investigational New Drugs - Category: Drugs & Pharmacology Source Type: research