Age-dependent impairment of adipose-derived stem cells isolated from horses.

CONCLUSIONS: Obtained data suggest that ASCs derived from horses older than 5 years old exhibited several molecular alternations which markedly limit their regenerative capacity. The results provide valuable information that allows for a better understanding of the molecular events occurring in ASCs in the course of aging and may help to identify new potential drug targets to restore their regenerative potential.
PMID: 31900232 [PubMed - in process]

Source: Cell Research - January 2, 2020 Category: Cytology Authors: Alicka M, Kornicka-Garbowska K, Kucharczyk K, Kępska M, Rӧcken M, Marycz K Tags: Stem Cell Res Ther Source Type: research