Ultrasound of infants exposed to Zika predicts long-term risk

Some infants who were exposed to the Zika virus in utero but who appeared normal...Read more on AuntMinnie.comRelated Reading: Brain abnormalities on CT, MRI indicate severe Zika Can prenatal ultrasound predict Zika infection outcomes? Digisonics launches website for Zika-related brain disease Zika's effects hard to detect on ultrasound, MRI MRI advances detection of Zika-related brain abnormalities
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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We report the case of an infant born with congenital Zika syndrome (CZS). During the largest Zika virus (ZIKV) outbreak in Peru, the mother presented with fever and rash that were confirmed to be due to ZIKV by real-time PCR. The infant was born with severe microcephaly. Imaging revealed corpus callosum dysgenesis, lissencephaly, ventriculomegaly, and calcifications. Mild hypertrophic cardiomyopathy with diastolic dysfunction was reported in the echocardiogram. Valgus deviation of the lower extremities and a left clubfoot were diagnosed at birth. The hip ultrasound showed incipient signs of Graf type II dysplasia. The find...
Source: Am J Trop Med Hyg - Category: Infectious Diseases Authors: Tags: Am J Trop Med Hyg Source Type: research
CONCLUSION: Prenatal ultrasound examination frequently detects structural findings associated with Zika virus infection; however, not all abnormalities are detected, and some may represent transient findings. As with other congenital infections, prenatal detection may vary with timing of infection, timing of ultrasound examination, technical expertise, and severity of abnormalities. The detection of Zika virus RNA in amniotic fluid in the included studies did not predict the risk for congenital Zika syndrome abnormalities in these cases, and clearance of Zika virus RNA from amniotic fluid appears possible after maternal in...
Source: Obstetrics and Gynecology - Category: OBGYN Authors: Tags: Obstet Gynecol Source Type: research
AbstractAxonal variants of Guillain –Barré syndrome (GBS) mainly include acute motor axonal neuropathy, acute motor and sensory axonal neuropathy, and pharyngeal-cervical-brachial weakness. Molecular mimicry of human gangliosides by a pathogen's lipooligosaccharides is a well-established mechanism forCampylobacter jejuni-associated GBS. New triggers of the axonal variants of GBS (axonal GBS), such as Zika virus, hepatitis viruses, intravenous administration of ganglioside, vaccination, and surgery, are being identified. However, the pathogenetic mechanisms of axonal GBS related to antecedent bacterial or viral...
Source: Journal of Neurology - Category: Neurology Source Type: research
Asisa Volz In 2015 Zika virus (ZIKV) emerged for the first time in South America. The following ZIKV epidemic resulted in the appearance of a clinical phenotype with microcephaly and other severe malformations in newborns. So far, mechanisms of ZIKV induced damage to the fetus are not completely understood. Previous data suggest that ZIKV may bypass the placenta to reach the fetus. Thus, animal models for ZIKV infection are important to facilitate studies about ZIKV infection during pregnancy. Here, we used ultrasound based imaging (USI) to characterize ZIKV induced pathogenesis in the pregnant Type I interferon recep...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
CONCLUSIONS: Early placentomegaly may represent the first sign of trans-placental contamination and should lead to an enhanced follow-up of these pregnancies. This article is protected by copyright. All rights reserved. PMID: 31773804 [PubMed - as supplied by publisher]
Source: The Ultrasound Review of Obstetrics and Gynecology - Category: Radiology Authors: Tags: Ultrasound Obstet Gynecol Source Type: research
Almost a quarter of fetal abnormalities are identified for the first time during...Read more on AuntMinnie.comRelated Reading: 5 trends shaping the future of global ultrasound Can prenatal ultrasound predict Zika infection outcomes? Samsung debuts ob/gyn ultrasound systems at ISUOG congress Virtual reality takes prenatal imaging to new heights Imaging detects telltale signs of Zika infection
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Structural abnormalities visible on the brain MRI and CT scans of infants with...Read more on AuntMinnie.comRelated Reading: Can prenatal ultrasound predict Zika infection outcomes? Zika's effects hard to detect on ultrasound, MRI MRI advances detection of Zika-related brain abnormalities Studies at RSNA offer new insights into Zika's spread Zika's rapid spread on MRI scans shocks researchers
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
The use of medical imaging during pregnancy has grown in the U.S. and Canada...Read more on AuntMinnie.comRelated Reading: In utero MRI on par with ultrasound for fetal brain evaluation How does chemo during pregnancy affect child development? Ultrasound in late pregnancy could reduce C-section rate Clinical rules reduce need for CTPA during pregnancy Can prenatal ultrasound predict Zika infection outcomes?
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
AbstractPurpose of ReviewEmerging infectious diseases have seen a record increase in prevalence, and understanding their management is critical in an increasingly global community. In this paper, we review current literature detailing the role of radiology in the diagnosis and treatment of the Ebola (EVD), Zika (ZVD), Chikungunya (CHIKF), H1N1, Middle East Respiratory (MERS), and Severe Acute Respiratory Syndrome (SARS) viruses.Recent FindingsComplex protocols are required to safely use portable imaging in EVD to prevent nosocomial spread of disease. In ZVD, antenatal ultrasound can detect fetal abnormalities early, allowi...
Source: Current Radiology Reports - Category: Radiology Source Type: research
Conclusion We found no differences in pregnancy or neonatal outcomes between women who tested positive and presumed positive for Zika virus during pregnancy. Testing of infants and placenta tissue after delivery was largely inconclusive. Improvement in testing for Zika virus infection is needed to determine which pregnancies are at risk for congenital anomalies. Further research is still needed to determine which children are at risk for poor neurodevelopmental outcomes related to Zika virus and how to best coordinate care among the immigrant population during a new disease epidemic. [...] Thieme Medical Publishers 33...
Source: American Journal of Perinatology - Category: Perinatology & Neonatology Authors: Tags: Original Article Source Type: research
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