New Evidence Supporting a Role of Hippocampus in the Development of Psychosis

The nature of cognitive dysfunction in schizophrenia and related disorders renders the hippocampus a particularly appealing research target in studies that attempt to uncover the mechanisms underlying conversion to psychosis. While comprising only approximately 1% of total gray matter volume in the adult brain (1), this small structure plays an indispensable role in a variety of cognitive functions known to be affected in schizophrenia, including declarative memory, learning, executive functioning, and emotional processing (2).
Source: Biological Psychiatry - Category: Psychiatry Authors: Tags: Commentary Source Type: research