Predicting Risk of Chemotherapy-induced Severe Neutropenia: A Pooled Analysis in Individual Patients Data with Advanced Lung Cancer

Neutropenia is a serious chemotherapy-induced hematologic toxicity in cancer patients. It is associated with both the risk of life-threatening infections and also chemotherapy dose reductions and delays that may compromise treatment outcomes [1]. In addition, studies have shown that health related quality of life is reduced in patients who develop neutropenia, especially those needing hospitalization [2,3]. Hence, it is important to try and estimate the risk of development of neutropenia in an attempt to try and minimize the impact on the patient ’s treatment plan.

Source: Lung Cancer - January 4, 2020 Category: Cancer & Oncology Authors: Xiaowen Cao, Apar Kishor Ganti, Thomas Stinchcombe, Melisa L. Wong, James C. Ho, Chen Shen, Yingzhou Liu, Jeffery Crawford, Herbert Pang, Xiaofei Wang Source Type: research