Effect of different A β Aggregates as Antigen on the Measure of Naturally Occurring Autoantibodies against Amyloid-β40/42 in IVIG.

CONCLUSION: The nAbs-Aβ40/42 content in the same IVIG is significantly different when measured with Aβ40/42 aggregated under different conditions. The nAbs-Aβ40/42 content in IVIG by antigen-dependent measures, like ELISA, is uncertain.
PMID: 31894747 [PubMed - as supplied by publisher]

Source: Current Alzheimer Research - January 1, 2020 Category: Neurology Authors: Cao H, Du X, Zeng R, Lv Z, Ye S, Jiang P, Wang Z, Ma L, Huang Y, Li C, Zhang R, Liu F Tags: Curr Alzheimer Res Source Type: research