Cancers, Vol. 12, Pages 127: High-Throughput Label-Free Isolation of Heterogeneous Circulating Tumor Cells and CTC Clusters from Non-Small-Cell Lung Cancer Patients

Conclusions: The Labyrinth device recovered heterogeneous CTCs in 100% and CTC clusters in 96% of patients with metastatic NSCLC. The majority of recovered CTCs/clusters were EpCAM−, suggesting that these would have been missed using traditional antibody-based capture methods.

Source: Cancers - January 2, 2020 Category: Cancer & Oncology Authors: Zeinali Lee Nadhan Mathur Hedman Lin Harouaka Wicha Zhao Palanisamy Hafner Reddy Kalemkerian Schneider Hassan Ramnath Nagrath Tags: Article Source Type: research