Incidence of tuberculosis in patients receiving anti-TNF therapy for rheumatic diseases: a systematic review

ConclusionThe incidence of TB in patients with rheumatic diseases exposed TNF inhibitor considering all countries was 9.62 cases per 1000 patients exposed. TB incidence was higher in South America and Asia compared with North America and Europe. Most cases occurred in the first XX months of use, and the pulmonary form predominated.Key Points•Higher incidence of tuberculosis in patients exposed to anti-TNF compared with the general population.• Higher incidence of TB in countries of South America and Asia compared with North America and Europe.
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research