Cone-beam breast CT features associated with HER2/neu overexpression in patients with primary breast cancer

ConclusionsCBBCT features could be used to prognosticate HER2 status independently, which are potentially complementary to histopathologic result and helpful in guiding biopsy.Key Points• Dmax, lobulation, ΔCT, and calcification morphology are independent predictors of HER2 status.• CBBCT features are superior to clinicopathologic features in HER2+/− discrimination.• CBBCT features are comparable with combination with clinicopathologic features in HER2+/− discrimination.

http://link.springer.com/10.1007/s00330-019-06587-w

Source: European Radiology - January 2, 2020 Category: Radiology Source Type: research