Differentiating factors of intra-articular injectables have a meaningful impact on knee osteoarthritis outcomes: a network meta-analysis

ConclusionHigh molecular weight HA was the only treatment to surpass the MID for both pain and function outcomes. Extended-release corticosteroids may provide additional clinical benefit over standard-release corticosteroids. Platelet-rich plasma demonstrated possibly beneficial results; however, wide confidence intervals and sensitivity analyses made the conclusions of efficacy uncertain.Level of evidenceLevel 1. Systematic review of level 1 evidence.

Source: Knee Surgery, Sports Traumatology, Arthroscopy - January 2, 2020 Category: Orthopaedics Source Type: research