PET-Based Human Dosimetry of 68Ga-NODAGA-Exendin-4, a Tracer for {beta}-Cell Imaging

Conclusion: Our human PET/CT-based dosimetric calculations show that the effective radiation doses from the novel tracer 68Ga-NODAGA-exendin-4 are very low for adults and children. The doses are lower than reported for other polypeptide tracers such as somatostatin analogs (2.1–2.6 mSv/100 MBq) and are beneficial for application as a research tool, especially when repeated examinations are needed.
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Clinical Source Type: research

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ConclusionThis study shows that many adults with T1D and T2D both need and want to talk with their diabetes health professionals about the emotional impact of diabetes. Those who were most willing to have this conversation were most in need of emotional support.
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research
Authors: Barkai L, Kiss Z, Rokszin G, Abonyi-Tóth Z, Jermendy G, Wittmann I, Kempler P Abstract Introduction: The aim of the present study was to assess changes in the incidence and prevalence of type 1 diabetes (T1DM) and type 2 diabetes (T2DM) in children and adolescents in Hungary during the period 2001 to 2016 in order to provide nationwide population-based epidemiology data on diabetes in youths aged 0-18 years. Material and methods: This was a retrospective cohort study of Hungarian children and adolescents aged 18 years or younger. Pharmacologically treated diabetes cases were obtained through a p...
Source: Archives of Medical Science - Category: General Medicine Tags: Arch Med Sci Source Type: research
This study compared extracted structured EHR data with chart review from endocrinologists’ health-care records at a large, academic ambulatory hospital in Toronto, Ontario.MethodsConsecutive chart review for the first 10 patients with either type 1 or type 2 diabetes seen between January 1, 2015 and March 1, 2016 was sampled for each of the 10 endocrinologists within the diabetes program, and electronic data extraction was also completed for a core set of structured diabetes care elements. Fisher exact test was used to determine differences in data availability between extracted EHR data and chart review.ResultsOut o...
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research
Abstract Diabetes is one of the most common chronic diseases among persons aged
Source: MMWR Morb Mortal Wkl... - Category: Epidemiology Authors: Tags: MMWR Morb Mortal Wkly Rep Source Type: research
e;zquiz Aguirre S, Sánchez Landa E Abstract INTRODUCTION: whether hypovitaminosis D is an overarching cause of increased mortality or a prognostic marker of poor health has not been well elucidated. OBJECTIVES: we sought to determine the association of serum 25-hydroxyvitamin D [25-(OH)-D3] levels with the clinical biochemical parameters and mortality risk in chronic diseases. METHODS: we reviewed the clinical charts and collected the clinical biochemical parameters of patients diagnosed with chronic conditions who had at least one 25-(OH)-D3 determination, with or without calcium and vitamin D su...
Source: Nutricion Hospitalaria - Category: Nutrition Authors: Tags: Nutr Hosp Source Type: research
THURSDAY, Feb. 13, 2020 -- From 2002 to 2015, there was a constant increase in the incidence of type 1 and type 2 diabetes among youth, according to research published in the Feb. 14 issue of the U.S. Centers for Disease Control and Prevention...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
The number of new cases of type 1 and type 2 diabetes in U.S. children and adolescents increased at constant rates from 2002 through 2015, and the rates of increase were generally higher in racial/ethnic minority populations than in whites.
Source: CDC Morbidity and Mortality Weekly Report - Category: American Health Tags: Children's Health Diabetes MMWR Morbidity & Mortality Weekly Report Youth Health Type 2 Diabetes Source Type: news
THURSDAY, Feb. 13, 2020 -- Diabetes among U.S. youths continued to rise from 2002 to 2015, especially for Asian children and teens, a new study says. Researchers analyzed type 1 and type 2 diabetes among 5- to 19-year-olds. They found rates were...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
This study was conducted to evaluate existing burden and unmet needs related to mealtime insulin (MTI) injection timing among adult Japanese patients with type 1 (T1D) and type 2 (T2D) diabetes. It also aimed to evaluate if a novel MTI could reduce this burden.
Source: Diabetes Research and Clinical Practice - Category: Endocrinology Authors: Source Type: research
AbstractType 2 diabetes mellitus (T2DM) is frequently misdiagnosed in children and treated as type 1 DM (T1DM) with insulin. Urinary C-peptide to creatinine ratio (UCPCR) can be used to measure ß cell function and endogenous insulin. We aimed to assess the value of UCPCR to differentiate T2DM from T1DM in pediatric patients. We assessed UCPCR from urine sample taken 2 h after lunch in 50 children with T1DM and 30 children with T2DM (duration of the disease ≥ 2 years and without rena l impairment). Fasting and postprandial C-peptide levels were also evaluated in all included children. Receiver oper...
Source: European Journal of Pediatrics - Category: Pediatrics Source Type: research
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