Tiotropium add-on therapy reduces seasonal peaks of asthma worsening in adults with symptomatic severe asthma

Despite the use of preferred controller therapies (including inhaled corticosteroids (ICS) with or without additional long-acting β2-agonists (LABAs)), a large proportion of patients with asthma have poor disease control, leaving them at risk of recurring symptoms and episodes of asthma exacerbations and worsening [1, 2]. Such problems can be triggered by many different environmental factors including pollutants, respiratory infections or allergens [3]. They may occur sporadically, but are often determined by the seasons, mirroring seasonal patterns of allergen exposure and prevalence of respiratory viral infection [3, 4].

Source: European Respiratory Journal - January 1, 2020 Category: Respiratory Medicine Authors: FitzGerald, J. M., Buhl, R., Casale, T. B., Jugovic, B., Zaremba-Pechmann, L., Halpin, D. M. G. Tags: Original Articles: Research letters Source Type: research