Causes of secondary non-alcoholic fatty liver disease in non-obese children below 10 years

Conclusion: GSD was the commonest cause of secondary NAFLD in Egyptian children<  10 years followed by HCV and CDS with higher degrees of steatosis in younger patients. The degree of fibrosis was significantly related to the degree of steatosis.What is Known:•Primary non-alcoholic fatty liver disease (NAFLD) is rare in children aged less than 10  years.•Secondary causes of NAFLD should be considered in patients who do not have traditional risk factors.What is New:•Glycogen storage disease, hepatitis C virus, and Chanarin-Dorfman syndrome are the commonest causes of secondary NAFLD in Egyptian children (<  10 years) with higher degrees of steatosis in younger patients.•The degree of liver fibrosis is significantly related to the degree of steatosis.

Source: European Journal of Pediatrics - January 1, 2020 Category: Pediatrics Source Type: research