Hot Line IV: Late-breaking trials on heart failure and acute coronary syndrome

(European Society of Cardiology) The blood pressure lowering drug aliskiren did not improve coronary artery disease when given to patients who had prehypertension, results of the Aliskiren Quantitative Atherosclerosis Regression Intravascular Ultrasound study reveal.
Source: EurekAlert! - Medicine and Health - Category: Global & Universal Source Type: news

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Hepatic cirrhosis is a potential severe complication of chronic heart failure and has major implications on treatment options. In general, patients with cirrhosis are considered ineligible for isolated cardiac transplantation. Therefore, proper diagnosis of cirrhosis is paramount. The aim of this retrospective study is to explore the diagnostic value of abdominal ultrasound, hepatosplenic scan and abdominal computed tomography scan (CT scan) for liver disease secondary to advanced heart failure.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: (564) Source Type: research
Condition:   Heart Failure Intervention:   Diagnostic Test: Lung ultrasound Sponsor:   Asan Medical Center Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
AbstractChorioangioma is a non-trophoblastic  benign vascular tumour of the placenta affecting fetal outcome. It has no malignant potential. It is usually diagnosed during the 2nd trimester. These are usually found on the fetal side of the placenta, close to the umbilical cord insertion site protruding into the amniotic cavity. Chorioangi omas can be small or large. Small tumours (less than 5 cm) usually have favourable outcome. Large chorioangiomas (more than 5 cm) usually have an unfavourable outcome and may cause maternal complications like pre-eclampsia, ...
Source: Journal of Fetal Medicine - Category: Perinatology & Neonatology Source Type: research
Conclusion: IVC ultrasound may have a limited value in the decision to hospitalise ADHF patients. But Maximum IVC diameter may be an ideal method for monitoring hypervolemic patients' volume status.Clinical Trials Identifier: NCT02725151. PMID: 32189575 [PubMed - as supplied by publisher]
Source: Acta Cardiologica - Category: Cardiology Tags: Acta Cardiol Source Type: research
This middle-aged man with no cardiac history but with significant history of methamphetamin and alcohol use presented with chest pain and SOB, worsening over days, with orthopnea.BP:143/99, Pulse 109, Temp 37.2 °C (99 °F), Resp (!) 32, SpO2 95%On exam, he was tachypneic and had bibasilar crackles.Here was his ED ECG:There is sinus tachycardia (rate about 114) with nonspecific ST-T abnormalities.There is a large peaked P-wave in lead II (right atrial enlargement)There is left axis deviation consistent with left anterior fascicular block.There are nonspecific ST-T abnormalities.There is no evidence of infarction or i...
Source: Dr. Smith's ECG Blog - Category: Cardiology Authors: Source Type: blogs
CONCLUSION: Depleting miR-195-5p and up-regulating CXCR4 alleviates cardiac function injury in mice with HF via inhibition of JAK/STAT signaling pathway activation. MiR-195-5p might be a potential candidate marker and therapeutic target for HF. PMID: 32155465 [PubMed - as supplied by publisher]
Source: International Immunopharmacology - Category: Allergy & Immunology Authors: Tags: Int Immunopharmacol Source Type: research
Discussion: The Z-track method minimizes fluid leakage from the puncture site. Injecting medication into the skin using this method is important to preventing post-procedure leaking. Once a needle has entered subcutaneous tissue and muscle, it opens a track that may not reseal immediately. There are also studies suggesting that Z tracks may reduce pain during injection. We suggest using the method during your paracentesis procedure.Z tracks are used for all kinds of intramuscular injections and can be applied to other sites on the body. Pull and press the skin and tissue 2 cm caudad to the deep abdominal wall and insert th...
Source: The Procedural Pause - Category: Emergency Medicine Tags: Blog Posts Source Type: blogs
CONCLUSION: RSH is a life-threatening condition that may cause acute abdominal pain, and endovascular embolization is a safe and effective treatment option that can be applied quickly in this patient group. PMID: 32185764 [PubMed - in process]
Source: Turkish Journal of Trauma and Emergency Surgery : TJTES - Category: Emergency Medicine Authors: Tags: Ulus Travma Acil Cerrahi Derg Source Type: research
Abstract Point-of-care ultrasonography (POCUS) is performed by a physician at the bedside and is standard practice in obstetric, emergency, and musculoskeletal medicine. When compared with formal sonography, POCUS is equivalent in screening for abdominal aortic aneurysm and as accurate in diagnosing deep venous thrombosis. POCUS has high accuracy for diagnosing pneumonia and detecting acute decompensated heart failure but is less accurate than computed tomography for identifying pulmonary embolism. POCUS confirmation of intrauterine pregnancy rules out an ectopic pregnancy. In the third trimester of high-risk preg...
Source: American Family Physician - Category: Primary Care Authors: Tags: Am Fam Physician Source Type: research
Current continuous-flow left ventricular assist devices (LVADs) decrease peripheral vascular pulsatility, which may contribute to side effects such as bleeding and thrombotic events. However, the actual impact of manipulating LVAD pump speed, revolutions per minute (rpm), on peripheral (brachial) pulsatility index (brachial PI), in patients with heart failure implanted with a HeartWare (HVAD) or HeartMateII (HMII) LVAD is unknown. Therefore, blood velocities (Doppler ultrasound) in the brachial artery were recorded and brachial PI calculated across rpm manipulations which spanned the acceptable clinical outpatient range: 3...
Source: ASAIO Journal - Category: Medical Devices Tags: Adult Circulatory Support Source Type: research
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