Viruses, Vol. 12, Pages 47: Discovery and Prevalence of Divergent RNA Viruses in European Field Voles and Rabbits
Viruses, Vol. 12, Pages 47: Discovery and Prevalence of Divergent RNA Viruses in European Field Voles and Rabbits
Viruses doi: 10.3390/v12010047
Authors:
Theocharis Tsoleridis
Joseph G. Chappell
Elodie Monchatre-Leroy
Gérald Umhang
Mang Shi
Malcolm Bennett
Rachael E. Tarlinton
C. Patrick McClure
Edward C. Holmes
Jonathan K. Ball
The advent of unbiased metagenomic virus discovery has revolutionized studies of virus biodiversity and evolution. Despite this, our knowledge of the virosphere, including in mammalian species, remains limited. We used unbiased metagenomic sequencing to identify RNA viruses in European field voles and rabbits. Accordingly, we identified a number of novel RNA viruses including astrovirus, rotavirus A, picorna-like virus and a morbilli-like paramyxovirus. In addition, we identified a sobemovirus and a novel luteovirus that likely originated from the rabbit diet. These newly discovered viruses were often divergent from those previously described. The novel astrovirus was most closely related to a virus sampled from the rodent-eating European roller bird (Coracias garrulous). PCR screening revealed that the novel morbilli-like paramyxovirus in the UK field vole had a prevalence of approximately 4%, and shared common ancestry with other rodent morbilli-like viruses sampled globally. Two novel rotavirus A sequences were detected in a UK field vole and a French rabbit, the latter with a prevalence of 5%. Finally, a highly divergent...
Source: Viruses - Category: Virology Authors: Theocharis Tsoleridis Joseph G. Chappell Elodie Monchatre-Leroy G érald Umhang Mang Shi Malcolm Bennett Rachael E. Tarlinton C. Patrick McClure Edward C. Holmes Jonathan K. Ball Tags: Article Source Type: research