Ruxolitinib prescription in myelofibrosis.

Ruxolitinib prescription in myelofibrosis.
Bull Cancer. 2013 Aug 28;
Authors: Lemal R, Robin M, Ravinet A, Cacheux V, Guièze R, Bay JO
Abstract
Ruxolitinib is a JAK/STAT inhibitor, which has demonstrated clinical benefits in patients with intermediate-2 and high-risk myelofibrosis. Moreover, first results of recent clinical trials show a trend to better overall survival with ruxolitinib, which allows to hope that we will soon be able to change the natural evolution of this poor outcome disease. With such results, ruxolitinib quickly obtained the Food and Drug Administration (FDA) approval in the United States of America. In France, ruxolitinib is now available, allowing its administration to symptomatic myelofibrosis patients.
PMID: 23985569 [PubMed - as supplied by publisher]

Source: Bulletin du Cancer - August 28, 2013 Category: Cancer & Oncology Authors: Lemal R, Robin M, Ravinet A, Cacheux V, Guièze R, Bay JO Tags: Bull Cancer Source Type: research