Desmoid ‐type fibromatosis arising from thoracotomy incision

Desmoid ‐type fibromatosis following thoracotomy is rare and has been previously reported only in
Source: Clinical Case Reports - Category: General Medicine Authors: Tags: CLINICAL IMAGE Source Type: research

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CONCLUSION: Graded increase of SMAD 2 expression from control,reactive lesions and OSMF were observed accentuating the role of SMAD signalling pathway in fibro genesis. Further this can be validated to generate effective antifibrotic targets. PMID: 32102517 [PubMed - in process]
Source: Asian Pacific Journal of Cancer Prevention - Category: Cancer & Oncology Tags: Asian Pac J Cancer Prev Source Type: research
This report discusses the oldest reported patient with HFS and is the first to describe the management of epidural anesthesia in a patient with HFS.
Source: A&A Case Reports - Category: Anesthesiology Tags: Case Reports Source Type: research
b S Abstract The management of desmoid-type fibromatosis has considerably evolved these last years, toward first-line active surveillance then systemic or local symptomatic treatment in case of aggressive tumor. Magnetic resonance imaging is the modality of choice in each of these treatment settings. It needs multiparametric approach taking into account mainly the tumor size, and T2-weighted signal that is correlated with histological composition and clinical behavior. A volumetric approach should be favored for the evaluation of tumor size change. The interest of paramagnetic contrast injection and tumor enhancem...
Source: Bulletin du Cancer - Category: Cancer & Oncology Authors: Tags: Bull Cancer Source Type: research
We present herein an evidence-based, joint global consensus guideline approach to the management of this disease focussing on: molecular genetics, indications for an active treatment, and available systemic therapeutic options.
Source: European Journal of Cancer - Category: Cancer & Oncology Authors: Tags: Review Source Type: research
AbstractCowden's syndrome (CS) is a rare autosomal dominant, hereditary multiorgan disease with higher risk for malignancies (breast, thyroid, endometrium). Mucocutaneous lesions occur in 90% of cases and are characterized by facial trichilemmomas,  oral mucosal papillomas and benign acral keratoses. A case of 39-year-old female patient with a chief complaint of " white spots " on the upper and lower attached gingiva accompanyed with skin changes on the face, hands and soles is presented. Her family medical history revealed that her mother had endometrial polyp and sister thyroid cancer. In her medical ...
Source: Acta Dermatovenerologica Croatica - Category: Dermatology Source Type: research
Abstract Pseudo-Meigs syndrome is defined as the secondary accumulation of ascites and hydrothorax associated with pelvic tumor other than benign ovarian tumor such as fibroma, which classically resolve upon surgical removal of the tumor. Here we report a case of pseudo-Meigs syndrome caused by a giant uterine leiomyoma, which was initially suspected to be ovarian cancer. A 37-year old nulliparous woman presented with a 5-month history of abdominal distension and anorexia. Abdominal ultrasonography revealed the presence of a giant cystic lesion and solid mass in the peritoneal cavity along with a massive ascites. ...
Source: Journal of Nippon Medical School - Category: Universities & Medical Training Authors: Tags: J Nippon Med Sch Source Type: research
Analyze for the first time the immunohistochemical expression in tooth germ (TG) ameloblastoma (AM), ameloblastic carcinoma (AC), ameloblastic fibroma (AF) and ameloblastic fibrosarcoma (AFS) of fatty acid synthase (fasn) and cyclooxygenase (cox-2), which are highly associated to tumorigenic events and poor prognosis in several types of cancer and also are promising chemotherapy targets.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - Category: ENT & OMF Authors: Source Type: research
Abstract We summarize here available data about systemic treatments of desmoids tumors, as well in adult patients as pediatric patients. Until 2018, the level of evidence associated with these treatments (NSAI, hormonal therapies, tyrosine kinase inhibitors, chemotherapy) was very low, based on retrospective studies or non-randomized phase 2 trials with limited number of cases. In 2018-2019, 2 large randomized trials have been published, including one large superiority phase 3 trial comparing sorafenib to placebo. This trial clearly demonstrates the clinical benefit of sorafenib over placebo (level of evidence IA)...
Source: Bulletin du Cancer - Category: Cancer & Oncology Authors: Tags: Bull Cancer Source Type: research
The resection of distal airways obstructing tumours is a traditional indication of therapeutic bronchoscopy. Lung cancer is the most frequent cause of the obstruction. Takeout procedures of the benign tumours, endobronchial carcinoids and endobronchial metastases are considerably less frequent. These tumours can be removed completely, some of them definitively. Present work analyses experience with these tumours in one tertiary bronchological centre. During the period from 1993 to 2018, 29.121 bronchoscopies were performed and 124 benign tumours, 19 typical carcinoids (G1 NET) and 35 endobronchial metastases were removed. ...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Interventional pulmonology Source Type: research
Authors: Abdulrahman Jnr GO, Das N, Lutchman Singh K Abstract Ovarian cancer is a lethal gynecological malignancy. Although CA-125 is commonly measured in women with adnexal mass, it is estimated that it only has a positive predictive value (PPV) of 69% and a negative predictive value (NPV) of 88% for the detection of ovarian cancer. The aim of this study was to investigate the diagnostic significance and predictive impact of thrombocytosis in women with suspected or confirmed ovarian cancer. This was a retrospective study of women who had surgery for adnexal mass over a 48-month period between September 2014 and S...
Source: Platelets - Category: Hematology Tags: Platelets Source Type: research
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