Diverging trends in incidence of HIV versus other sexually transmitted infections in HIV-negative MSM in Amsterdam

Objectives: We investigated changes in incidence rates of HIV and sexually transmitted infections (STIs) and trends in sexual behavior in MSM from 2009 to 2017. Design: Open prospective cohort study. Methods: HIV-negative MSM enrolled in the Amsterdam Cohort Studies were included. Participants semiannually completed a questionnaire on sexual behavior and were tested for HIV-1, syphilis, and urethral, anal and pharyngeal chlamydia and gonorrhea. Time trends in incidence rates were analyzed using exponential survival models. Results: During follow-up, 42 of 905 MSM acquired HIV. The HIV incidence rate was 1.9/100 person-years [95% confidence interval (CI) 1.0–3.7] in 2009 and decreased to 0.5/100 person-years (95% CI 0.2–1.4) in 2017 (P = 0.03). The largest decrease was observed in participants aged at least 35 years (P = 0.005), while the trend remained stable in 18–34 year olds (P = 0.4). The incidence rate for any bacterial STI was 16.8/100 person-years (95% CI 13.4–21.0) in 2010, and increased to 33.1/100 person-years (95% CI 29.0–37.9) in 2017 (P 
Source: AIDS - Category: Infectious Diseases Tags: Epidemiology and Social Source Type: research