Factors Associated With Frequent Opioid Use in Children With Acute Recurrent and Chronic Pancreatitis

Objectives: The aim of the study was to understand the association of frequent opioid use with disease phenotype and pain pattern and burden in children and adolescents with acute recurrent (ARP) or chronic pancreatitis (CP). Methods: Cross-sectional study of children
Source: Journal of Pediatric Gastroenterology and Nutrition - Category: Gastroenterology Tags: Original Articles: Pancreatology Source Type: research

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AbstractChronic pancreatitis is an inflammatory process of the pancreas characterized by progressive parenchyma destruction, resulting in pain and exocrine and endocrine insufficiency. In the advanced stages the diagnosis by imaging is usually straightforward, while in the early phases of the disease there can be a paucity of findings at imaging, thus making an early diagnosis challenging. Different imaging modalities can have a role in the initial diagnosis and in the longitudinal follow-up of patients affected by chronic pancreatitis, also enabling to assess the complications of the disease. Radiography, Ultrasonography,...
Source: Abdominal Imaging - Category: Radiology Source Type: research
Recurrent acute and chronic pancreatitis are increasingly recognized in childhood. Etiologies are vastly different in children compared with adults and mostly involve genetic and anatomical factors with negligible contribution of environmental risks. Pediatric acute recurrent pancreatitis (ARP) and chronic pancreatitis (CP) have significant impact on quality of life with high healthcare costs. Children with these conditions suffer from recurrent acute or chronic abdominal pain and they endure multiple emergency room visits, hospitalizations, procedures, and surgeries. Diagnostic methods are being developed; treatment optio...
Source: Journal of Pediatric Gastroenterology and Nutrition - Category: Gastroenterology Tags: Topic of the Month Source Type: research
Pain, the hallmark symptom of chronic pancreatitis, remains difficult to treat, particularly given the unclear mechanism of pain in this disease.1 Pain likely results from an interplay between pancreatic ductal and parenchymal hypertension in combination with neural remodeling and sensitization, making it particularly challenging to identify which patients will respond to which treatments.2
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: Original article Source Type: research
This study aimed to systematically explore the efficacy and safety of rhubarb/EEN in SAP patients. METHODS: We performed searches in EMBASE, PubMed, Medline, Cochrane Library, Chinese Biomedicine Literature Database (SinoMed), Chinese Scientific Journal Database (VIP), Chinese National Knowledge Infrastructure (CNKI), and Wanfang database to identify relevant literature comparing rhubarb/EEN with EEN for SAP. RESULTS: Eleven randomized controlled trials (724 patients) were included. Meta-analysis showed significantly shorter length of hospital stay (days) (mean difference [MD], -4.49; 95% CI, -6.09 to -2.90; P
Source: JPEN Journal Of Parenteral And Enteral Nutrition - Category: Nutrition Authors: Tags: JPEN J Parenter Enteral Nutr Source Type: research
Conditions:   Chronic Pancreatitis;   Inflammatory Bowel Diseases;   Hepatitis;   NASH - Nonalcoholic Steatohepatitis;   Acute Pancreatitis;   Rheumatoid Arthritis;   Diabetes Mellitus;   Dyslipidemias;   Multiple Sclerosis;   Irritable Bowel Syndrome;   Chronic Pain;   Chronic Diseas e;   Chronic Kidney Diseases;   Crohn Disease;   Celiac Disease;   Biliary Cirrhosis;   Bile Acid Synthesis Defect;   Gastritis;   Cholecys...
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Pancreatic pseudocysts are seen both in acute and chronic pancreatitis. Prevalence of pancreatic pseudocyst in chronic pancreatitis is 20% to 40% and is most commonly seen in alcoholic chronic pancreatitis. Intracystic hemorrhage from a pseudoaneurysm is a rare and potentially a lethal complication of pancreatic pseudocyst with an incidence of less than 10%. We herein present a case of a 42-year-old male with a past medical history of chronic alcoholic pancreatitis, stable pseudocyst in the tail of pancreas, alcohol abuse and seizures who presented with abdominal pain and acute anemia had this rare complication of hemorrhagic pseudocyst.
Source: The American Journal of Emergency Medicine - Category: Emergency Medicine Authors: Source Type: research
Genetic testing, evaluation and treatment of pain syndromes, and the possible value of treatment algorithms for improved chronic pancreatitis management.Location : The University Club, 123 University Place, Pittsburgh, PA 15260Date : 7/27/2016 8:00:00 AM
Source: NIDDK Meetings and Events - Category: Endocrinology Source Type: events
We present the case of a 52-year-old male who was admitted with obstructive jaundice and weight loss. He presented with a mass lesion in the porta hepatis mimicking hilar cholangiocarcinoma. The patient underwent extended right hepatectomy with hepaticojejunostomy. Severe liver failure developed postoperatively, and the patient underwent liver transplantation. The resected specimen showed infiltration of IgG4 positive plasma cells in the liver hilum, and immunohistochemical staining demonstrated a ratio of IgG4/IgG-positive plasma cells of more than 40 %. Postoperative serological testing showed elevated levels o...
Source: Tidsskrift for den Norske Laegeforening - Category: General Medicine Authors: Tags: Tidsskr Nor Laegeforen Source Type: research
Publication date: Available online 19 February 2020Source: European Journal of RadiologyAuthor(s): Mahya Faghih, Vikesh K. Singh, Mashayekhi R, Parekh VS, Michael A. Jacobs, Atif Zaheer
Source: European Journal of Radiology - Category: Radiology Source Type: research
Publication date: Available online 19 February 2020Source: European Journal of RadiologyAuthor(s): Yu Liu, Hua-Liang Chen, Zhao-Shen Li, Dan Wang, Liang-Hao Hu
Source: European Journal of Radiology - Category: Radiology Source Type: research
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