Acquired long QT syndrome in chronic kidney disease patients.

Acquired long QT syndrome in chronic kidney disease patients. Ren Fail. 2020 Nov;42(1):54-65 Authors: Liu P, Wang L, Han D, Sun C, Xue X, Li G Abstract Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in chronic kidney disease (CKD) patients. QT interval prolongation is a congenital or acquired condition that is associated with an increased risk of torsade de pointes (TdP), sudden cardiac death (SCD), and all-cause mortality in the general population. The prevalence of acquired long QT syndrome (aLQTS) is high, and various acquired conditions contribute to the prolonged QT interval in patients with CKD. More notably, the prolonged QT interval in CKD is an independent risk factor for SCD and all-cause mortality. In this review, we focus on the epidemiological characteristics, risk factors, underlying mechanisms and treatments of aLQTS in CKD, promoting the management of aLQTS in CKD patients. PMID: 31878817 [PubMed - in process]
Source: Renal Failure - Category: Urology & Nephrology Tags: Ren Fail Source Type: research

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Authors: Musio F Abstract INTRODUCTION: Anemia has and will continue to be a central theme in medicine particularly as clinicians are treating a burgeoning population of complex multi-organ system processes. As a result of multiple randomized controlled trials (RCTs), meta-analyses, and societal recommendations overly restrictive paradigms and under-administration of erythropoiesis stimulating agents (ESAs) have likely been followed by clinicians among all specialties. AREAS COVERED: A review of anemia in the context of chronic kidney disease, hematologic malignancies and cancer is presented with focus on the e...
Source: Expert Review of Hematology - Category: Hematology Tags: Expert Rev Hematol Source Type: research
Authors: Kim MS, Moon JS, Kim MJ, Seong MW, Park SS, Ko JS Abstract Hereditary fructose intolerance (HFI) is an autosomal recessive disorder caused by a mutation in the aldolase B gene. HFI patients exhibit nausea, vomiting, abdominal pain, hypoglycemia, and elevated liver enzymes after dietary fructose exposure. Chronic exposure might lead to failure to thrive, liver failure, renal failure, and, eventually, death. HFI usually manifests in infants when they are being weaned off of breastmilk. Because HFI has an excellent prognosis when patients maintain a strict restrictive diet, some patients remain undiagnosed du...
Source: Gut and Liver - Category: Gastroenterology Tags: Gut Liver Source Type: research
Publication date: Available online 8 October 2020Source: Hematology/Oncology and Stem Cell TherapyAuthor(s): M.M. Sulaiman, A.I. Ladu, A.M. Abba, A.A. Bukar
Source: Hematology Oncology and Stem Cell Therapy - Category: Cancer & Oncology Source Type: research
Authors: Zou Y, Zhang L, Zhou H, Yang Y, Yang M, Di J PMID: 33028124 [PubMed - in process]
Source: Renal Failure - Category: Urology & Nephrology Tags: Ren Fail Source Type: research
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Source: Renal Failure - Category: Urology & Nephrology Tags: Ren Fail Source Type: research
Conditions:   Stenosis; Valve;   Renal Failure;   Renal Insufficiency Intervention:   Diagnostic Test: TAVI without contrast Sponsor:   University of Sao Paulo General Hospital Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Long QT Syndrome Intervention:   Drug: Lumacaftor / Ivacaftor, Orkambi® Oral Tablet Sponsor:   Istituto Auxologico Italiano Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Stenosis; Valve;   Renal Failure;   Renal Insufficiency Intervention:   Diagnostic Test: TAVI without contrast Sponsor:   University of Sao Paulo General Hospital Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Long QT Syndrome Intervention:   Drug: Lumacaftor / Ivacaftor, Orkambi® Oral Tablet Sponsor:   Istituto Auxologico Italiano Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
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