Viral hepatitis B and C co-infection with Human Immunodeficiency Virus among adult patients attending selected highly active anti-retroviral therapy clinics in Nigeria's capital.

This study determined the seroprevalence of HIV co-infection with the two viruses among patients attending three major hospitals in the Federal Capital Territory, Nigeria. From February to July 2019, 311 sera samples were collected from HIV positive patients and screened for Hepatitis B and C infection. Immunochromatographic and ELISA techniques for HBsAg and HCV were used. Socio-demographic features and responses to risk factors were obtained using questionnaires. Patients' data and results obtained were analyzed with SPSS version 25. The prevalence of HIV/HBV/HCV, HIV/HBV, and HIV/HCV co-infection were 0.64%, 6.43%, and 3.86%, respectively. The triple infection and both co-infections were preponderant among females than males, with a prevalence rate of 0.64%, 3.85%, 2.57%, and 0%, 2.57%, 1.29%, respectively. People aged 31-40 years had the highest triple infection (0.64%) and HIV/HCV infection rate (2.57%), while patients aged 21-30 years had the highest HBV co-infection (3.22%) rates. Widowed patients had the most co-infection rate in all cases. High-risk behavior indicated that there was a significant association between blood donation/reception and engagement in unprotected sex and HIV/HBV/HCV co-infection. The other risk factors revealed no significant effect (p > .05). There was generally a low rate of exposure to associated risk factors. This study highlighted the endemicity of hepatitis virus co-infection in Abuja and the existence of few reports of HIV co-infe...
Source: Journal of Immunoassay and Immunochemistry - Category: Biochemistry Tags: J Immunoassay Immunochem Source Type: research