Synthesis and evaluation of 5-imino-4-thioxoimidazolidin-2-one derivatives as antibacterial and antifungal agents.

CONCLUSION: 5-Imino-4-thioxoimidazolidin-2-ones were obtained in 77-90% yields with excellent purity. The antibacterial and antifungal activities suggest that some of the imidazole derivatives possess significant antimicrobial activity against B. subtilis, K. pneumonia and C. albicans and moderate activity against S. aureus. PMID: 31880248 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31880248?dopt=Abstract

Source: Medicinal Chemistry - December 25, 2019 Category: Chemistry Authors: Abbas SY, El-Sharief MAMS, Al-Harbi RAK, El-Gammal EW, El-Sharief AMS Tags: Med Chem Source Type: research

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