The Outcomes of Portal Vein Reconstruction With Vein Graft Interposition in Pediatric Liver Transplantation for Small Children With Biliary Atresia

Conclusions. VG interposition for PV reconstruction in LDLT appears to be a feasible alternative option with acceptable outcomes for patients with BA. Achieving sufficient PV flow is essential to preventing PVCs after LDLT.
Source: Transplantation - Category: Transplant Surgery Tags: Original Clinical Science—Liver Source Type: research

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Since a 1989 report demonstrating successful living donor liver transplantation (LDLT), living donors have been increasingly used to overcome the disparity between organ supply and demand, especially in the cases of pediatric patients. Although short-term graft outcomes after LDLT have improved significantly because of progress in surgical techniques and immunosuppression, biliary stricture (BS) remains the Achilles heel of pediatric LDLT and is the major cause of significant long-term morbidity. BS results in poor quality of life or even in graft loss after LDLT, with a reported incidence of BS after pediatric LDLT of 10%...
Source: Transplantation - Category: Transplant Surgery Tags: Commentaries Source Type: research
ConclusionUsing a collateral vein as an alternative autologous venous conduit is a feasible option that can have durable success.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
Conclusions: Microvascular hepatic artery anastomosis in pediatric patients undergoing living donor liver transplantation is associated with a low hepatic artery complication rate and excellent long-term liver graft function. Collaboration between microsurgeons and transplant surgeons can significantly reduce technical complications and improve patient outcomes. CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV.
Source: Plastic and Reconstructive Surgery - Category: Cosmetic Surgery Tags: Reconstructive: Trunk: Original Articles Source Type: research
ConclusionTIPS placement in pediatric patients has high technical success with excellent resolution of variceal hemorrhage and ascites. TIPS revision was required in nearly half of the cohort, with hepatic encephalopathy common after shunt placement.
Source: Pediatric Radiology - Category: Radiology Source Type: research
Authors: Alobaidi R, Anton N, Cave D, Moez EK, Joffe AR Abstract AIM: To determine potentially modifiable predictors of early outcomes after liver transplantation in children of age
Source: World Journal of Hepatology - Category: Gastroenterology Tags: World J Hepatol Source Type: research
In January, 2018, Academic Press published my bookPrecision Medicine and the Reinvention of Human Disease. This book has an excellent " look inside " at itsGoogle book site, which includes the Table of Contents. In addition, I thought it might be helpful to see the topics listed in the Book's index. Note that page numbers followed by f indicate figures, t indicate tables, and ge indicate glossary terms.AAbandonware, 270, 310geAb initio, 34, 48ge, 108geABL (abelson leukemia) gene, 28, 58ge, 95 –97Absidia corymbifera, 218Acanthameoba, 213Acanthosis nigricans, 144geAchondroplasia, 74, 143ge, 354geAcne, 54ge, 1...
Source: Specified Life - Category: Information Technology Tags: index jules berman jules j berman precision medicine Source Type: blogs
In adult liver transplantation, renoportal anastomosis (RPA) has been introduced as a useful technique for patients with grade 4 portal vein thrombosis and a splenorenal shunt. Here, we report a pediatric case in which RPA allowed a left lateral lobe living donor liver transplantation (LDLT) despite portal vein thrombosis and a large splenorenal shunt. At 36 days old, the patient underwent a Kasai operation for biliary atresia. At 17 months old, she underwent LDLT because of repetitive cholangitis. Pretransplant examinations revealed a large splenorenal shunt and portal vein thrombosis. Simple end-to-end portal reconstruct...
Source: Case Reports in Gastroenterology - Category: Gastroenterology Source Type: research
A 9-year-old girl was admitted to the oral pathology department presenting green teeth coloration. The patient's medical history noted that after 20 days of birth she was diagnosed with biliary atresia. She underwent surgery to restore the bile flow (hepatoportoenterostomy); however, she had persistent conjugated hyperbilirubinemia. At 3 years of age, she underwent liver transplantation and progressed to a thrombosis of the portal vein and splenomegaly. Medications at presentation included tacrolimus as immunosuppressive agent to prevent organ transplant rejection and prednisone.
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: Rediscovering the Physical Exam Source Type: research
In adult liver transplantation, renoportal anastomosis (RPA) has been introduced as a useful technique for patients with grade 4 portal vein thrombosis and a splenorenal shunt. Here, we report a pediatric case in which RPA allowed a left lateral lobe living donor liver transplantation (LDLT) despite portal vein thrombosis and a large splenorenal shunt. At 36 days old, the patient underwent a Kasai operation for biliary atresia. At 17 months old, she underwent LDLT because of repetitive cholangitis. Pretransplant examinations revealed a large splenorenal shunt and portal vein thrombosis. Simple end-to-end portal reconstruct...
Source: Case Reports in Gastroenterology - Category: Gastroenterology Source Type: research
Conclusion: Strong consideration should be given to the use of technical variant allografts in small recipients with biliary atresia requiring liver transplantation. This article is protected by copyright. All rights reserved.
Source: Liver Transplantation - Category: Transplant Surgery Authors: Tags: Original Article Source Type: research
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