Deletion of low-density lipoprotein-related receptor 5 inhibits liver Cancer cell proliferation via destabilizing Nucleoporin 37

LRP5/6 are co-receptors in Wnt/ β-catenin pathway. Recently, we discovered multiple β-catenin independent functions of LRP5/6 in tumor cells and in the diseased heart. Nucleoporin 37 (NUP37) is an important com...

Source: Cell Communication and Signaling - December 27, 2019 Category: Molecular Biology Authors: Jinxiao Chen, Da Wo, En Ma, Hongwei Yan, Jun Peng, Weidong Zhu, Yong Fang and Dan-ni Ren Tags: Research Source Type: research