Effects of Physical Exercise on the Expression of MicroRNAs: A Systematic Review
Silva, FCd, Iop, RdR, Andrade, A, Costa, VP, Gutierres Filho, PJB, and Silva, Rd. Effects of physical exercise on the expression of microRNAs: A systematic review 34(1): 270–280, 2020—Studies have detected changes in the expression of miRNAs after physical exercise, which brings new insight into the molecular control of adaptation to exercise. Therefore, the objective of the current systematic review of experimental and quasiexperimental studies published in the past 10 years was to assess evidence related to acute effects, chronic effects, and both acute and chronic effects of physical exercise on miRNA expression in humans, as well as its functions, evaluated in serum, plasma, whole blood, saliva, or muscle biopsy. For this purpose, the following electronic databases were selected: MEDLINE by Pubmed, SCOPUS, Web of Science, and also a manual search in references of the selected articles to April 2017. Experimental and quasiexperimental studies were included. Results indicate that, of the 345 studies retrieved, 40 studies met the inclusion criteria and two articles were included as a result of the manual search. The 42 studies were analyzed, and it can be observed acute and chronic effects of physical exercises (aerobic and resistance) on the expression of several miRNAs in healthy subjects, athletes, young, elderly and in patients with congestive heart failure, chronic kidney disease, diabetes mellitus type 2 associated with morbid obesity, prediabetic, and pati...
ConclusionThe practice of health promotion behaviour varies among patients, individually tailored interventions and motivation is needed.
AbstractAim of testosterone replacement therapy (TRT) is to improve symptoms and signs of testosterone deficiency including decreased libido, erectile dysfunction, depressed mood, anaemia, loss of muscle and bone mass, by increasing serum testosterone levels to physiologic range. TRT has been used in the last 70 years and overtime, numerous preparations and formulations have been developed to improve pharmacokinetics (PKs) and patient compliance. The routes of delivery approved for use in western world include buccal, nasal, sub dermal, transdermal, and intramuscular (IM). The aim of this narrative review is to describe an...
ConclusionThe association of antibiotic and surgical therapy seems to be more effective compared to each one alone. The lack of comparison studies and randomized controlled trials makes it difficult to give information about the efficacy of the different management therapies.
ConclusionsCaffeine was a marker for increased intake of calories and decreased intake of key nutrients. When discussing dietary intake in early childhood, practitioners should screen for nutrient deficiency in young children and recommend limiting the intake of caffeinated foods and beverages.
Putting your child to bed after 9 p.m. is linked to an increase in weight, a new study says, but science is still pondering all the reasons why.
The unregulated sale and purchase of prescription medication isare prohibited by law and by Craigslist policy, but this doesn't seem to deter some people.Medscape Medical News
Conditions: Obesity; Weight Loss Interventions: Drug: Botulinum toxin type A; Behavioral: Weight Management Program Sponsor: Tan Tock Seng Hospital Recruiting
Condition: Healthy Intervention: Sponsor: Arkansas Children's Hospital Research Institute Recruiting
Conditions: Obesity; Thyroid; Surgery--Complications Intervention: Sponsor: University of Cagliari Completed
Condition: Gestational Diabetes Mellitus in Pregnancy Intervention: Behavioral: moderate-intensity lifestyle intervention Sponsor: Rashid Centre for Diabetes and Research Recruiting
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