Opioids for chronic osteoarthritis pain. An updated systematic review and meta ‐analysis of efficacy, tolerability and safety in randomized placebo‐controlled studies of at least four weeks double‐blind duration

ConclusionsTolerability of opioids is low and efficacy is not clinically relevant in controlled studies from four to 24  weeks for osteoarthritis pain.

Source: European Journal of Pain - December 25, 2019 Category: Anesthesiology Authors: Patrick Welsch, Frank Petzke, Petra Klose, Winfried H äuser Tags: REVIEW ARTICLE Source Type: research