Induced pluripotent stem cell line (PEIi003-A) derived from an apparently healthy male individual

Publication date: January 2020Source: Stem Cell Research, Volume 42Author(s): Nina V. Fuchs, Maximilian Schieck, Michaela Neuenkirch, Christiane Tondera, Heike Schmitz, Doris Steinemann, Gudrun Göhring, Renate KönigAbstractInduced pluripotent stem cells (iPSCs) are a useful tool to investigate pathomechanistic and cellular processes due to their differentiation potential into different somatic cell types in vitro. Here, we have generated iPSCs from an apparently healthy male individual using an integration-free reprogramming method. The resulting iPSCs are pluripotent and display a normal karyotype. Furthermore, we demonstrate that this iPSC line can be differentiated into all three germ layers.
Source: Stem Cell Research - Category: Stem Cells Source Type: research