The cost-effectiveness of guideline-driven use of drug-eluting stents: propensity-score matched analysis of a seven-year multicentre experience.
Conclusions: The cost-effectiveness of DES compared with BMS increased with increasing risk profile of patients from those who had 1, 2, to ≥3 indications for a DES. When compared with BMS, DES was least cost effective among patients with '0' indications for a DES. Based on these results, selective use of DES implantation is supported. These findings may be useful for evidence-based clinical decision-making. PMID: 31870180 [PubMed - as supplied by publisher]
There is ongoing uncertainty regarding the safety and efficacy of unfractionated heparin and bivalirudin when used for systemic anticoagulation in patients undergoing primary percutaneous coronary intervention (PPCI). This paper reports 12-month mortality from the HEAT-PPCI randomised trial.
(American College of Cardiology) An international clinical trial that used genetic testing to guide which antiplatelet medication was given to patients following percutaneous coronary intervention (PCI) did not meet its stated goal for cutting in half the incidence of serious adverse cardiovascular events, such as heart attack and stroke, in the year following the procedure, according to study results presented at the American College of Cardiology's Annual Scientific Session Together with World Congress of Cardiology (ACC.20/WCC).
ConclusionsUsing CQR and UQR allowed for heterogenous assessment of covariates along the adherence distribution, which is not possible with the traditional logistic regression method. The UQR framework revealed patients who initiate prasugrel or ticagrelor generally have lower adherence compared to those treated with branded clopidogrel, especially around the 30th quantile. Using these methods in other types of data sets, such as electronic health records, could help strengthen our results to develop policies to improve antiplatelet adherence in a targeted population.
Conclusions: The hemorrhagic risk was found to be greater with prasugrel than clopidogrel in real-world patients, including Japanese patients. PMID: 32218694 [PubMed - as supplied by publisher]
Authors: Aung AT, Chan SP, Kyaing TT, Lee CH Abstract Introduction: Compared to clinic blood pressure (BP), sleep-time BP and non-dipping BP pattern are better predictors of target organ damage and cardiovascular sequalae.Aim: In a retrospective study, we determined whether diabetes mellitus (DM) status is associated with high sleep-time BP and non-dipping pattern.Methods: We analyzed 1092 patients who underwent ambulatory BP monitoring between 2015 and 2017 in a tertiary cardiology institution. During a 24-hour period, BP was automatically measured every 15 minutes between 7:00 AM and 11:59 PM and every 30&nb...
Monocyte to High Density Lipoprotein Ratio (MHR) is a new marker that has been associated with major adverse cardiovascular outcomes among STEMI patients. We sought to strengthen the association between MHR an...
Nephrotic syndrome and Giant cell arthritis concurrently occurring after percutaneous transluminal angioplasty for renal artery stenosis . Clin Nephrol. 2020 Mar 26;: Authors: Ishizaki Y, Nishizono R, Sato Y, Ishikawa T, Kitamura K, Fujimoto S Abstract An elderly Japanese woman with bilateral renal artery occlusion who developed massive proteinuria after unilateral percutaneous transluminal renal angioplasty (PTRA) is reported. She had a history of percutaneous coronary intervention and subsequently developed refractory hypertension. She was diagnosed with renovascular hypertension caused by bilater...
The outcomes of percutaneous coronary intervention (PCI) with new-generation drug-eluting stents (DES) in patients with proximal left anterior descending (P-LAD) coronary-artery lesions appear similar to those seen in patients with lesions in other segments, according to data from three clinical trials.Reuters Health Information
Publication date: Available online 25 March 2020Source: American Heart JournalAuthor(s): Yong-Hoon Yoon, Jung-Min Ahn, Do-Yoon Kang, Hanbit Park, Sang-Cheol Cho, Pil Hyung Lee, Seung-Ho Hur, Won-Jang Kim, Chul Soo Park, Bong-Ki Lee, Jung-Won Suh, Jung Han Yoon, Jae Woong Choi, Ki-Sik Kim, Si Wan Choi, Su Nam Lee, Seung-Jung Park, Duk-Woo Park
Conditions: Coronary Artery Calcification; Left Main Coronary Artery Disease Intervention: Device: Left main stenting with intravascular lithotripsy Sponsors: St George's, University of London; St George's University Hospitals NHS Foundation Trust; Shockwave Medical, Inc. Not yet recruiting