Effects of human umbilical cord mesenchymal stem cells on inflammatory factors and miR-181a in T lymphocytes from patients with systemic lupus erythematosus.

CONCLUSION: UC-MSCs have showed certain immunomodulatory and inhibitory effects in vitro on T lymphocytes from SLE patients, which could potentially be a beneficial treatment of the disease. UC-MSCs may up-regulate miR-181a and down-regulate inflammation-related gene expression. PMID: 31870216 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31870216?dopt=Abstract

Source: Lupus - December 22, 2019 Category: Rheumatology Authors: Zheng B, Zhang P, Yuan L, Chhetri RK, Guo Y, Deng D Tags: Lupus Source Type: research