Therapeutic drug monitoring-guided high dose meropenem therapy of a multidrug resistant Acinetobacter baumannii - A case report.

Conclusions: Therapeutic drug monitoring-guided meropenem may be a sound new therapeutic option in eradicating multidrug resistant Acinetobacter and offer a novel therapeutic option in the field of personalized medicine. PMID: 31871885 [PubMed]
Source: Respiratory Care - Category: Respiratory Medicine Authors: Tags: Respir Med Case Rep Source Type: research

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The objective of this study was to evaluate the effects of intramuscular (IM) and subcutaneous (SC) sites for ovarian grafts in goats by evaluating follicular morphology and activation, preantral follicle and stromal cell densities, tissue DNA fragmentation, collagen types I and III depositions, and graft revascularizations. Ovarian cortical tissue was transplanted in IM or SC sites and recovered 7 or 15 days post-transplantation. There was a greater percentage of developing follicles and lesser follicular and stromal cell densities in all grafted tissues as compared to ovarian tissues of the control group. The stromal cel...
Source: Animal Reproduction Science - Category: Zoology Authors: Tags: Anim Reprod Sci Source Type: research
Condition:   Live Donors, Ethnic Minorities, Transplantation Intervention:   Behavioral: Video and questionnaire Sponsor:   University Hospitals Coventry and Warwickshire NHS Trust Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Acute Myeloid Leukemia;   AML, Childhood Interventions:   Drug: Cytarabine;   Drug: Daunorubicin;   Drug: Erwinase;   Drug: Etoposide;   Drug: Gemtuzumab ozogamicin;   Procedure: Stem cell transplantation (SCT);   Drug: Sorafenib Sponsor:   Emory University Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
ConclusionsThis is the first report of livebirth after use of robotic ‐assisted laparoscopy in uterus transplantation and is thereby a proof‐of‐concept of use of minimal invasive surgery in this new type of transplantation.
Source: Acta Obstetricia et Gynecologica Scandinavica - Category: OBGYN Authors: Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
Authors: Massoud O Abstract Introduction: The recent availability of highly effective hepatitis C medications, with a cure rate approaching 100%, has created a wide range of questions and uncertainties.Areas covered: The most recent data around hepatitis C virus (HCV) elimination will be reviewed. In addition, the impact of HCV cure or sustained virologic response (SVR) on the risk for hepatocellular carcinoma (HCC) development will be discussed. Although the terms 'SVR' and 'cure' are used interchangeably, there are little data to support that they are actually the same. In this review, we will shed some ligh...
Source: Expert Review of Gastroenterology and Hepatology - Category: Gastroenterology Tags: Expert Rev Gastroenterol Hepatol Source Type: research
Authors: Testino G, Balbinot P, Leone S, Pellicano R PMID: 32218429 [PubMed - as supplied by publisher]
Source: Minerva Gastroenterologica e Dietologica - Category: Gastroenterology Tags: Minerva Gastroenterol Dietol Source Type: research
Authors: Leone S, Pellicano R, Testino G, Caputo F PMID: 32218428 [PubMed - as supplied by publisher]
Source: Minerva Gastroenterologica e Dietologica - Category: Gastroenterology Tags: Minerva Gastroenterol Dietol Source Type: research
Some viable organs have not been recovered from deceased donors in Ontario in the wake of the COVID-19 pandemic, as hospitals in the province temporarily scale back procedures that aren't deemed essential, according to a leading transplant specialist in Toronto.
Source: CBC | Health - Category: Consumer Health News Tags: News/Canada/Ottawa Source Type: news
ConclusionsTherapeutic drug monitoring-guided meropenem may be a sound new therapeutic option in eradicating multidrug resistant Acinetobacter and offer a novel therapeutic option in the field of personalized medicine.
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species), represent a group of multidrug-resistant (MDR) bacteria that demonstrate the ability to escape antimicrobial treatments. These organisms are highly responsible for nosocomial and community-acquired infections, such as ventilator-associated pneumonia and S. aureus induced diabetic foot infection. Notably, P. aeruginosa contributes directly to the high mortality rate of cystic fibrosis (CF) chronic lung infections.
Source: International Journal of Antimicrobial Agents - Category: Drugs & Pharmacology Authors: Tags: Short Communication Source Type: research
More News: Acinetobacter | Antibiotic Therapy | Cystic Fibrosis | Intensive Care | Lung Transplant | Multidrug Resistance | Respiratory Medicine | Transplant Surgery | Transplants