Therapeutic drug monitoring-guided high dose meropenem therapy of a multidrug resistant Acinetobacter baumannii - A case report.
Conclusions: Therapeutic drug monitoring-guided meropenem may be a sound new therapeutic option in eradicating multidrug resistant Acinetobacter and offer a novel therapeutic option in the field of personalized medicine. PMID: 31871885 [PubMed]
The objective of this study was to evaluate the effects of intramuscular (IM) and subcutaneous (SC) sites for ovarian grafts in goats by evaluating follicular morphology and activation, preantral follicle and stromal cell densities, tissue DNA fragmentation, collagen types I and III depositions, and graft revascularizations. Ovarian cortical tissue was transplanted in IM or SC sites and recovered 7 or 15 days post-transplantation. There was a greater percentage of developing follicles and lesser follicular and stromal cell densities in all grafted tissues as compared to ovarian tissues of the control group. The stromal cel...
Condition: Live Donors, Ethnic Minorities, Transplantation Intervention: Behavioral: Video and questionnaire Sponsor: University Hospitals Coventry and Warwickshire NHS Trust Recruiting
Conditions: Acute Myeloid Leukemia; AML, Childhood Interventions: Drug: Cytarabine; Drug: Daunorubicin; Drug: Erwinase; Drug: Etoposide; Drug: Gemtuzumab ozogamicin; Procedure: Stem cell transplantation (SCT); Drug: Sorafenib Sponsor: Emory University Recruiting
ConclusionsThis is the first report of livebirth after use of robotic ‐assisted laparoscopy in uterus transplantation and is thereby a proof‐of‐concept of use of minimal invasive surgery in this new type of transplantation.
Authors: Massoud O Abstract Introduction: The recent availability of highly effective hepatitis C medications, with a cure rate approaching 100%, has created a wide range of questions and uncertainties.Areas covered: The most recent data around hepatitis C virus (HCV) elimination will be reviewed. In addition, the impact of HCV cure or sustained virologic response (SVR) on the risk for hepatocellular carcinoma (HCC) development will be discussed. Although the terms 'SVR' and 'cure' are used interchangeably, there are little data to support that they are actually the same. In this review, we will shed some ligh...
Authors: Testino G, Balbinot P, Leone S, Pellicano R PMID: 32218429 [PubMed - as supplied by publisher]
Authors: Leone S, Pellicano R, Testino G, Caputo F PMID: 32218428 [PubMed - as supplied by publisher]
Some viable organs have not been recovered from deceased donors in Ontario in the wake of the COVID-19 pandemic, as hospitals in the province temporarily scale back procedures that aren't deemed essential, according to a leading transplant specialist in Toronto.
ConclusionsTherapeutic drug monitoring-guided meropenem may be a sound new therapeutic option in eradicating multidrug resistant Acinetobacter and offer a novel therapeutic option in the field of personalized medicine.
ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species), represent a group of multidrug-resistant (MDR) bacteria that demonstrate the ability to escape antimicrobial treatments. These organisms are highly responsible for nosocomial and community-acquired infections, such as ventilator-associated pneumonia and S. aureus induced diabetic foot infection. Notably, P. aeruginosa contributes directly to the high mortality rate of cystic fibrosis (CF) chronic lung infections.