Duration of pharmacological thromboprophylaxis after outpatient endovenous laser ablation: a propensity score-matched analysis.
CONCLUSION: Using propensity score-matched analysis we showed that pharmacological thromboprophylaxis after EVLA seems to be equally effective with 3 days or 10 days of treatment with a similar success rate and safety profile. Undoubtedly, a large randomised control trial, ideally including a group without pharmacological thromboprophylaxis, is needed to draw more definitive conclusions on the optimal duration of pharmacological post-EVLA thromboprophylaxis. PMID: 31869428 [PubMed - in process]
Publication date: Available online 28 March 2020Source: Journal of Clinical NeuroscienceAuthor(s): Tugba Ozsoy-Unubol, Yeliz Bahar-Ozdemir, Ilker Yagci
Authors: Zhang Y, Bi L, Hu Z, Cao W, Zhuang D Abstract It has been found that>90% of oral cancer patients suffer from squamous cell carcinoma (SCC). The 5-year survival rate of SCC is ~50%, despite the availability of different treatments. Sonodynamic therapy (SDT) has been developed as a novel therapy for cancer, resisting bacterial infection and inhibiting atherosclerotic plaque progression. The present study investigated the efficacy of hematoporphyrin monomethyl ether (HMME)-mediated SDT on the A-253 epidermoid cancer cell line. The cytotoxicity of HMME and the survival rate of cells following SDT were exami...
Authors: Shibayama Y, Wada N, Baba S, Obara S, Sakai H, Usubuchi H, Terae S, Nakamura A, Atsumi T Abstract Patients with primary aldosteronism (PA) are complicated by metabolic syndrome more frequently than those without PA. Hyperaldosteronism has been reported to be associated with a higher prevalence of non-alcoholic fatty liver disease (NAFLD). We aimed to clarify the risk factors for hepatic steatosis in the two subtypes of PA, comparing the status of hepatic steatosis in each of these subtypes. This was a retrospective observational study. We enrolled patients with an aldosterone producing adenoma (APA) (n = 3...
Conclusions: Cytoreductive nephrectomy should no longer be considered the standard of care in patients with T3b or T4, or node-positive, and metastatic rcc. Eligible patients should be treated with systemic therapy and have their primary tumour removed only after review at a multidisciplinary case conference (mcc). Adjuvant sunitinib after surgery is not recommended. Patients with venous tumour thrombus should be considered for surgical intervention. Patients with T3, T4, or node-positive utuc should have their tumour removed without delay. Decisions concerning lymph node dissection should be done at a mcc and be based on ...
Conclusions: In the Canadian setting, the acceptance of rebiopsy on progression was high. Multiple rebiopsies were clinically feasible and could increase the yield for T790M mutation. The incidence of complications was low despite the most common site for rebiopsy being lung. PMID: 32218657 [PubMed - as supplied by publisher]
Why isn't this discussed more? Why isn't there an entire AAN journal dedicated to this? Many days I see more functional patients/consults than "normal" patients. I'm becoming more and more cynical, I almost assume each patient is functional before meeting them. These patients are ticking time bombs for the clinician. It's drilled into us about appropriate use of testing/imaging but where do you even begin with their ridiculous amount of symptoms? Of course the correct answer is to order as... Functional neurology is going to single handedly burn me out.
Benign M üllerian papillomas have been described in patients as a rare tumor of the female genital tract. Symptoms typically arise as pre-pubertal vaginal bleeding with findings of a polypoid mass originating in the cervix or vagina. However, a vaginal squamous papilloma in a menarchal patient has not yet b een described in the literature. We will describe a case of recurrent squamous vaginal lesion in a 12 year old female.
We present baseline results of an ongoing longitudinal study examining menstrual suppression and QoL in GM youth. The objective of the current analysis was to examine menstrual related symptoms and menstrual suppression method choice in GM youth at time of method initiation.
While squamous cell papillomas (SCPs) are commonly reported in the literature to occur in adults at the larynx, oral cavity, oropharynx and anus, recent reports of occurrence in the vaginal canal are rare. With the rise in HPV related cancers, as well as the increased incidence of high risk types of HPV in SCP, it is becoming more important to be able to detect and genotype HPV for management of such cases. Furthermore, recognition of this entity is important in the evaluation of any vaginal mass causing prepubertal bleeding.
Ehlers-Danlos Syndrome (EDS) is a connective tissue disorder resulting in abnormal collagen synthesis leading to skin, joint, ligament, blood vessel and organ abnormalities. Studies in adults show an association with heavy menstrual bleeding, dysmenorrhea, and other gynecologic concerns, but there are no studies looking at gynecologic problems an adolescent population with EDS. We aimed to survey gynecologic complaints and management in a pediatric and adolescent population with EDS.