A bigger fish for palaeontogists to fry…

A chance find in a quarry led to the discovery that Leedsichthys problematicus grew up to 50ft long – double previous estimatesAn international team of scientists has uncovered the remains of the world's largest fish. The 50ft Leedsichthys problematicus swam the oceans of the Jurassic era more than 160m years ago, sweeping up shoals of plankton through giant, mesh-covered gills. Leedsichthys was eventually wiped out by the same catastrophe that killed the dinosaurs 66m years ago.The discovery by the team – led by Professor Jeff Liston of the National Museums of Scotland – is intriguing because it reveals that just as dinosaurs on land were going through major changes which saw the appearance of animals of vast dimensions – creatures that included Diplodocus, Apatosaurus and Brachiosaurus – reptiles in the sea had also started to grow to vast proportions in the Jurassic."The process is known as gigantism," said Liston. "It was known about in land animals at the time but we had no way of knowing if a parallel process occurred in the oceans. We now know that it did – though the reason for appearance of these gigantic beasts, both on land and in the water, is not clear at present."Pieces of Leedsichthys fossils were first found by the British collector Alfred Leeds in 1889. Similar remains were subsequently found at other sites, from northern Germany to Normandy, Mexico and the Atacama desert in Chile. However, knowledge of ...
Source: Guardian Unlimited Science - Category: Science Authors: Tags: Evolution Dinosaurs Editorial The Observer Fossils Zoology Science Source Type: news

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Endocrine Practice,Volume 25, Issue 4, Page 396-398, April 2019.
Source: Endocrine Practice - Category: Endocrinology Authors: Source Type: research
r A Abstract The heterogenous catagory "specific types of diabetes due to other causes" encompasses disturbances in glucose metabolism due to other endocrine disorders such as acromegaly or hypercortisolism, drug-induced diabetes (e. g. antipsychotic medications, glucocorticoids, immunosuppressive agents, highly active antiretroviral therapy (HAART)), genetic forms of diabetes (e. g. Maturity Onset Diabetes of the Young (MODY), neonatal diabetes, Down Syndrome, Klinefelter Syndrome, Turner Syndrome), pancreatogenic diabetes (e. g. postoperatively, pancreatitis, pancreatic cancer, haemochromatosis, ...
Source: Wiener Klinische Wochenschrift - Category: General Medicine Authors: Tags: Wien Klin Wochenschr Source Type: research
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research
Erratum to "Impact of Long-Acting Somatostatin Analogues on Glucose Metabolism in Acromegaly: A Hospital-Based Study". Int J Endocrinol. 2019;2019:1987417 Authors: Shen M, Wang M, He W, He M, Qiao N, Ma Z, Ye Z, Zhang Q, Zhang Y, Yang Y, Cai Y, ABuDuoReYiMu Y, Lu Y, Lu B, Shou X, Wang Y, Ye H, Li Y, Li S, Zhao Y, Cao X, Zhang Z Abstract [This corrects the article DOI: 10.1155/2018/3015854.]. PMID: 30962806 [PubMed - in process]
Source: International Journal of Endocrinology - Category: Endocrinology Tags: Int J Endocrinol Source Type: research
This study was supported in part by the National Cancer Center Research and Development Fund (25-A-7 and 28-A-8); Health and Labor Science Research Grants for Clinical Research, Japan; and joint research funding from Takeda Pharmaceutical Co, Ltd.; Noile-Immune Biotech Inc.; Ono Pharmaceutical Co., Ltd.; BrightPath Biotherapeutics Co., Ltd.; and Sysmex Co., Ltd. This study was performed as part of a research program of the Project for Development of Innovative Research on Cancer Therapeutics (P-Direct), Ministry of Education, Culture, Sports, Science and Technology of Japan. Conflict of Interest Statement TN, TS, and TY ...
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
In conclusion, our results suggest that BZ may have an important role in the resistance of pituitary adenomas to the pharmacological treatment with somatostatin analogs. PMID: 30986651 [PubMed - as supplied by publisher]
Source: Environmental Research - Category: Environmental Health Authors: Tags: Environ Res Source Type: research
Publication date: Available online 4 April 2019Source: The Lancet Diabetes &EndocrinologyAuthor(s): Eva C Coopmans, Aart J van der Lely, Joppe J Schneiders, Sebastian J C M M Neggers
Source: The Lancet Diabetes and Endocrinology - Category: Endocrinology Source Type: research
Conclusions Diagnosis of acromegaly requires active medical involvement and awareness. Intervention of patient-experts in medical schools may help to be more aware of this disease. Endocrinologists caring for patients with acromegaly should also address the catastrophic dimension of the patient's experience and initiate the narrative to help them to put it into words for preventing harmful consequences such as social isolation and QoL impairment, but also anxiety or depression. PMID: 30939451 [PubMed - as supplied by publisher]
Source: European Journal of Endocrinology - Category: Endocrinology Authors: Tags: Eur J Endocrinol Source Type: research
In this study, we compared the effect of a trematode species on shell size and morphology in adult individuals of the intertidal mussels Perumytilus purpuratus (>20 mm) collected from two local populations of contrasting environmental regimes experienced in central-southern Chile. Our field data indicates that in both study locations, parasitized mussels evidenced higher body sizes (shell length, total weight and volume) as compared with non-parasitized. In addition, parasitized mussels from the southern location evidenced thinner shells than non-parasitized ones and those collected from central Chile, suggesting geog...
Source: International Journal for Parasitology: Parasites and Wildlife - Category: Parasitology Source Type: research
CONCLUSIONS: Independently of disease control, PEG in monotherapy or combined with SSAs seems to improve glucose metabolism, reducing FPG, HbA1c, FPI and HOMA-I. PMID: 30869797 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - Category: Endocrinology Authors: Tags: J Clin Endocrinol Metab Source Type: research
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