Transfusion-Free Cranial Vault Remodeling: A Novel, Multifaceted Approach

Background: Approximately one in 2000 babies are born with craniosynostosis, and primary open repair is typically performed before 1 year of age. Historically, the procedure has been associated with nearly 100 percent transfusion rates. To decrease the rates of transfusion, the authors’ center has developed a novel multimodal blood conservation protocol. Methods: The authors administered their standard of care to children aged 1 year or younger undergoing primary repair of craniosynostosis between 2008 and 2014. In 2014, the authors implemented the following protocol: (1) preoperative erythropoietin and ferrous sulfate, (2) local anesthetic with epinephrine infiltration of the incision, (3) PlasmaBlade incision and subgaleal dissection, (4) hypervolemic hemodilution, and (5) intravenous tranexamic acid. Procedures performed before the protocol implementation served as controls. The authors performed classic fronto-orbital advancement with anterior cranial vault remodeling for coronal and metopic craniosynostosis. For lambdoid and sagittal craniosynostosis, barrel stave osteotomies, cranial base outfracture, and interposition bone grafting were performed. Results: A total of 279 children with a mean age of 6 months who had craniosynostosis repairs were included. One hundred forty-five underwent repair before the authors’ protocol, and 134 had repairs during the authors’ blood conservation protocol. Both groups were similar in demographics. Overall blo...
Source: Plastic and Reconstructive Surgery - Category: Cosmetic Surgery Tags: Pediatric/Craniofacial: Original Articles Source Type: research

Related Links:

Publication date: Available online 6 April 2020Source: Journal of Ginseng ResearchAuthor(s): Xiaoying Li, Xianhui Cheng, Baosheng Liao, Jiang Xu, Xu Han, Jinbo Zhang, Zhiwei Lin, Lianghai Hu
Source: Journal of Ginseng Research - Category: Complementary Medicine Source Type: research
Publication date: Available online 14 January 2020Source: Journal of Acupuncture and Meridian StudiesAuthor(s): Renuka T. Rudra, Vitaly Gordin, Lihua Xu
Source: Journal of Acupuncture and Meridian Studies - Category: Complementary Medicine Source Type: research
Publication date: Available online 21 November 2019Source: Journal of Acupuncture and Meridian StudiesAuthor(s): Maria P. Volpato, Izabela C.A. Breda, Ravena C. de Carvalho, Caroline de Castro Moura, Laís L. Ferreira, Marcelo L. Silva, Josie R.T. Silva
Source: Journal of Acupuncture and Meridian Studies - Category: Complementary Medicine Source Type: research
Publication date: Available online 7 April 2020Source: Integrative Medicine ResearchAuthor(s): Hyesook Lee, Hyun Hwang-Bo, Seon Yeong Ji, Min Yeong Kim, So Young Kim, Minji Woo, Young-Sam Keum, Jeong Sook Noh, Joung-Hyun Park, Bae-Jin Lee, Gi-Young Kim, Eui Kyun Park, Young-Chae Chang, You-Jin Jeon, Yung Hyun Choi
Source: Integrative Medicine Research - Category: Complementary Medicine Source Type: research
Publication date: Available online 6 April 2020Source: Revista Española de Cardiología (English Edition)Author(s):
Source: Revista Espanola de Cardiologia - Category: Cardiology Source Type: research
Publication date: Available online 7 April 2020Source: Indian Heart JournalAuthor(s): Kewal Kanabar, Dinakar Bootla, Navjyot Kaur, C.R. Pruthvi, Darshan Krishnappa, Krishna Santosh, Vivek Guleria, Manoj Kumar Rohit
Source: Indian Heart Journal - Category: Cardiology Source Type: research
Publication date: Available online 6 April 2020Source: Indian Heart JournalAuthor(s): Samit Ghosal, Binayak Sinha, Jignesh Ved, Mansij Biswas
Source: Indian Heart Journal - Category: Cardiology Source Type: research
Publication date: Available online 6 April 2020Source: Indian Heart JournalAuthor(s): Krishna Kumar Mohanan Nair, Narayanan Namboodiri, Ajitkumar Valaparambil
Source: Indian Heart Journal - Category: Cardiology Source Type: research
Publication date: Available online 6 April 2020Source: Canadian Journal of CardiologyAuthor(s): Mohammad I. Zia, Venkat Ramanan, Idan Roifman, Kim A. Connelly, Graham A. Wright, Nilesh R. Ghugre
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
Publication date: Available online 6 April 2020Source: Canadian Journal of CardiologyAuthor(s): Philip Moons, Koen Luyckx, Corina Thomet, Werner Budts, Junko Enomoto, Maayke A. Sluman, Chun-Wei Lu, Jamie L. Jackson, Paul Khairy, Stephen C. Cook, Shanthi Chidambarathanu, Luis Alday, Katrine Eriksen, Mikael Dellborg, Malin Berghammer, Bengt Johansson, Andrew S. Mackie, Samuel Menahem, Maryanne Caruana, Gruschen Veldtman
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
More News: Anesthesia | Anesthesiology | Babies | Blood Transusion | Children | Craniofacial Surgery | Gastroschisis Repair | Pediatrics | Plastic Surgery