Lessons from radiochemotherapy and modern image-guided adaptive brachytherapy followed by hysterectomy.

CONCLUSIONS: Due to high severe toxicity, RCT and IGABT with dose escalation followed by completion hysterectomy don't seem compatible. No benefit and increased severe late morbidity were observed. Combined intracavitary/interstitial technique is mandatory in large target volume at brachytherapy.
PMID: 31864683 [PubMed - as supplied by publisher]

Source: Gynecologic Oncology - December 17, 2019 Category: Cancer & Oncology Authors: Varela Cagetti L, Zemmour C, Minsat M, Lambaudie E, Houvenaeghel G, Provansal M, Cappiello MA, Rua S, Jauffret C, Ferré M, Mailleux H, Gonzague L, Tallet A Tags: Gynecol Oncol Source Type: research