The influence of dopaminergic polymorphisms on selective stopping.

This study aimed to investigate for the first time the influence of two relevant dopaminergic polymorphisms (in COMT and DRD2 genes) on stimulus-selective stopping in a sample of 529 adults. Results showed that although none of these polymorphisms (neither individually nor in combination) modulate the latency of the stop process in each strategy (the stop-signal reaction time), the choice of strategy was influenced by their interaction. These results suggest that dopaminergic polymorphisms might influence strategy adoption in selective stopping paradigms, which constitutes a novel finding.
PMID: 31863847 [PubMed - as supplied by publisher]

Source: Behavioural Brain Research - December 17, 2019 Category: Neurology Authors: Rincón-Pérez I, Echeverry-Alzate V, Sánchez-Carmona AJ, Bühler KM, Hinojosa JA, López-Moreno JA, Albert J Tags: Behav Brain Res Source Type: research