Mortality and causes of death among people suspected of driving under the influence and testing positive for multiple substances.

Conclusions: DUIMS indicates higher mortality, and DUIMS' profiles in causes of death differ from the general population. Elevated risk for, for instance, suicidal, accidental and violent death among those using multiple substances highlights the need to also pay attention to causes of death other than poisoning/overdose. PMID: 31856686 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Public Health - Category: International Medicine & Public Health Authors: Tags: Scand J Public Health Source Type: research

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Source: BMJ Comments - Category: General Medicine Source Type: forums
This study compares the effect of Helicobacter (H.) pylori and Lactobacillus (L.) acidophilus on the cytokine profile of PBMCs of 5 men with abdominal aortic aneurysm (AAA) and 5 men with normal/insignificant angiography, CT-Scan and ultrasonography results in the single-culture and in the co-culture with HUVECs. IL-2, IL-4, IL-5, IL-6, IL-9, IL-10, IL-13, IL-17A, IL-17 F, IL-21, IL-22, IFN-γ and TNF-α were measured in culture supernatants using a commercial fluorescent-labeled-bead assay.In general, CagA+ H. pylori-extract induced higher production of IFN-γ, IL-13 and IL-21 by PBMCs. Treatment of ...
Source: Comparative Immunology, Microbiology and Infectious Diseases - Category: Infectious Diseases Source Type: research
Authors: Ma Q, Shao Y, Chen W, Quan C, Zhu Y, Xu X, Zhou Z, Wang S Abstract Aim: To investigate whether cervical cancer (CC) and cervical intraepithelial neoplasia (CIN) can be screened by analyzing gene expression profiling of peripheral blood. Methods: RNA-sequencing analysis of blood was performed on 11 CC patients, 21 CIN patients and 19 healthy controls (H). Fifty-nine genes were validated by quantitative real-time PCR using blood samples from 46 H, 83 CC and 32 CIN patients. Results: There were significant differences in the expression levels of six genes between CC and H, five genes between CIN and H and fou...
Source: Future Medicine: Biomarkers in Medicine - Category: Internal Medicine Tags: Biomark Med Source Type: research
Authors: Deng Z, Wu J, Xu S, Chen F, Zhang Z, Jin A, Wang J Abstract Exosomes have appeared as fundamental vehicle-modulated crosstalk among various cells in the tumor microenvironment. The systematic understanding of exosomes in gastric cancer (GC) enhances our comprehension about the tumor growth, metastasis, chemoresistance and diagnosis of cancers. The versatile functions of exosomes provide reasonable explanations about the propensity for GC metastasis. The selectively enriched components, especially some exosomal miRNAs, are potential noninvasive biomarkers for sensitive and specific GC diagnosis. Given the c...
Source: Future Medicine: Biomarkers in Medicine - Category: Internal Medicine Tags: Biomark Med Source Type: research
This study aimed to quantitatively grasp the structure of support for balancing cancer treatment and work among occupational health nurses (OHNs) with the current implementation status. The anonymous questionnaire was designed based on the findings of our previous qualitative study and distributed to OHNs. The degrees of support implementation for workers with cancer, superiors and colleagues, and human resource managers were assessed for each item. Factor analysis of support items was conducted, and Wilcoxon signed-rank test was carried out to compare the support scores between the factors. Support for workers with cancer...
Source: Industrial Health - Category: Occupational Health Tags: Ind Health Source Type: research
Publication date: Available online 19 February 2020Source: Mechanisms of Ageing and DevelopmentAuthor(s): Cui Chen, Min Zhou, Yuchen Ge, Xiaobo WangAbstractAging is a biological phenomenon in which the structure and function of organisms declining with the increasing of age. It has become a major risk factor of human diseases, including diabetes, cancers, cardiovascular diseases and neurodegenerative diseases. Silencing information regulator 2 related enzyme 1(sirtuin1, SIRT1) is an NAD+-dependent deacetylase, which has been reported to be involved in the regulation of cellular senescence and aging. The expression of SIRT1...
Source: Mechanisms of Ageing and Development - Category: Geriatrics Source Type: research
According to the latest numbers, roughly 9 million Americans — 4% of U.S. adults — use prescription sleep aids, or medications that can help with insomnia and other sleep issues. And now, some of the most popular prescription sleep drugs must carry stronger safety warnings. In April, the Food and Drug Administration (FDA) mandated black-box warnings — which the agency uses to “call attention to serious or life-threatening risks” — on three sedative-hypnotic sleep aids: eszopiclone (often sold under the brand name Lunesta), zaleplon (Sonata) and zolpidem (Ambien). Hypnotic drugs, which ar...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Drugs Source Type: news
(CNN) — For the first time on record the odds of accidentally dying from an opioid overdose in the United States are now greater than those of dying in an automobile accident. The grim finding comes from the National Safety Council which analyzed preventable injury and fatality statistics from 2017. The NSC also found the lifetime odds of death for this form of overdose were greater than the risk of death from falls, pedestrian incidents, drowning and fire. Examining a variety of federal and state data the NSC found the lifetime odds of dying from an accidental opioid overdose were 1 in 96. For motor vehicle accident...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News CNN Local TV opioid crisis opioids Source Type: news
There was a 28% increase in the rate of firearm deaths among U.S. children between 2013 and 2016, according to areport published today in theNew England Journal of Medicine.In all, there were more than 20,000 deaths among children and adolescents in the United States in 2016, and the majority —60%—resulted from injury-related causes. Motor vehicle crashes were the leading cause of death for children and adolescents, representing 20% of all deaths, followed by firearm-related injuries (15%), and malignant neoplasm, or cancer (9%).Declines in deaths from infectious disease or cancer have been eclipsed by increase...
Source: Psychiatr News - Category: Psychiatry Tags: adolescents CDC WONDER children Edward W. Campion firearm deaths homicide New England Journal of Medicine Rebecca Cunningham suicide Source Type: research
McLean Hospital Guest Blogger Hilary Smith Connery, MD, PhD Self-inflicted injury is now the 8th leading cause of mortality, while suicide is the 10th leading cause of death in the United States. That's a stunning number of people dying by their own hand in one form or another, and in addition to galvanizing public health prevention efforts, these statistics pose an urgent need to identify root causes and more effective treatment systems. Treatment works, but beyond having access to appropriate medical and psychological help, the social environment is critical to creating successful recovery opportunities for those suff...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
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