Impact and safety of radiotherapy boost to extra-mesorectal lymph nodes in rectal cancer

ConclusionDespite the well documented negative prognostic impact of LPN metastasis, we observed promising outcomes for LPN+ patients treated with an additional radiation boost. Our results suggest that radiotherapy boost to clinically involved, un-resected LPN is an effective treatment approach with limited toxicity. Additional studies are needed to optimize treatment strategy for this unique patient subset.
Source: Practical Radiation Oncology - Category: Cancer & Oncology Source Type: research