5-hydroxymethylcytosine profiles in circulating cell-free DNA associate with disease burden in children with neuroblastoma.

CONCLUSIONS: cfDNA 5-hmC profiles in children with neuroblastoma correlate with metastatic burden and warrants development as a biomarker of treatment response and outcome.
PMID: 31852832 [PubMed - as supplied by publisher]

Source: Clinical Cancer Research - December 17, 2019 Category: Cancer & Oncology Authors: Applebaum MA, Barr EK, Karpus J, West-Szymanski DC, Oliva M, Sokol EA, Zhang S, Zhang Z, Zhang W, Chlenksi A, Salwen HR, Wilkinson E, Dobratic M, Grossman RL, Godley LA, Stranger BE, He C, Cohn SL Tags: Clin Cancer Res Source Type: research