Viruses, Vol. 12, Pages 14: Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System?
Viruses, Vol. 12, Pages 14: Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System? Viruses doi: 10.3390/v12010014 Authors: Marc Desforges Alain Le Coupanec Philippe Dubeau Andréanne Bourgouin Louise Lajoie Mathieu Dubé Pierre J. Talbot Respiratory viruses infect the human upper respiratory tract, mostly causing mild diseases. However, in vulnerable populations, such as newborns, infants, the elderly and immune-compromised individuals, these opportunistic pathogens can also affect the lower respiratory tract, causing a more severe disease (e.g., pneumonia). Respiratory viruses can also exacerbate asthma and lead to various types of respiratory distress syndromes. Furthermore, as they can adapt fast and cross the species barrier, some of these pathogens, like influenza A and SARS-CoV, have occasionally caused epidemics or pandemics, and were associated with more serious clinical diseases and even mortality. For a few decades now, data reported in the scientific literature has also demonstrated that several respiratory viruses have neuroinvasive capacities, since they can spread from the respiratory tract to the central nervous system (CNS). Viruses infecting human CNS cells could then cause different types of encephalopathy, including encephalitis, and long-term neurological diseases. Like other well-recognized neuroinvasive human viruses, respiratory viruses may damage the CNS a...
ConclusionsAmong uninsured and underinsured asthma patients with GAD and/or MDD who were initiated on a single antidepressant, those who were titrated to achieve target doses had reduced risk of severe asthma exacerbations and lower number of asthma ‐related outcomes than those who were not optimized to achieve target doses.
[New Zimbabwe] A Chinese owned hotel, Golden Peacock Villa, has stopped all bookings from visitors coming from countries that have been affected by the coronavirus as a control measure to ensure their facility is safe for other visitors.
An American couple who traveled in the Diamond Princess cruise ship that's docked at the Daikoku Pier Cruise Terminal in Yokohama, Japan, have had their hopes of coming home dashed. Rebecca Frasure has tested positive for the coronavirus, which means she has to remain in quarantine at a nearby hospital. CNN's Will Ripley reports.
Outside of China, the Diamond Princess is the site of the biggest coronavirus outbreak.
A mother-of-two finds strength in her communityThis month marked the first time I ’ve ever been to a queue-free post office, and been served by a man wearing gloves in the service station. “We’ve been told to use antibacterial gel every half hour too,” he told me. Supermarkets are quieter than usual, but with no signs of panic buying – unless hand sanitiser counts. “I went to five shops and couldn’t find any,” a neighbour texted me. Dozens of people are “self-isolating”, and it’s a risky place for secret affairs because of the chance everyone you’ve be...
You have to use soap and water, and you should wash your hands for about 20 seconds. One way to estimate this is to sing the whole of the Happy Birthday To You song, twice, says DR MOSLEY.
The number of new cases of a coronavirus in China fell slightly on Sunday, more than three weeks after the outbreak's epicenter was locked down, and a Chinese tourist died from the virus in France, the first fatality in Europe.