Affective temperaments (TEMPS-A) in panic disorder and healthy probands - genetic modulation by 5-HTT variation.

Conclusions: Dysthymic, cyclothymic, irritable and notably anxious temperament could serve as valuable intermediate phenotypes in efforts to unravel neurobiological, particularly serotonin system related genetic pathomechanisms associated with PD and potentially contribute to a panel of vulnerability markers guiding early targeted preventive interventions. PMID: 31852378 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31852378?dopt=Abstract

Source: The World Journal of Biological Psychiatry - December 17, 2019 Category: Psychiatry Authors: Schiele MA, Herzog K, Kollert L, Böhnlein J, Repple J, Rosenkranz K, Leehr EJ, Ziegler C, Lueken U, Dannlowski U, Pauli P, Arolt V, Zwanzger P, Deckert J, Erfurth A, Domschke K Tags: World J Biol Psychiatry Source Type: research