Clinical Associations of Uveitis in Axial Spondyloarthritis Group and Ankylosing Spondylitis Group: Do They Represent the Same Disease?

Conclusions Axial SpA represents a spectrum of diseases. Its clinical associations with uveitis should be distinguished from those of traditional AS.
Source: JCR: Journal of Clinical Rheumatology - Category: Rheumatology Tags: Original Articles Source Type: research

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CONCLUSIONS: TAK does co-occur with IBD, AS and less frequently with BS in about 1/5 of the patients, at least in a hospital setting. There is no clear temporal pattern. The high prevalence of inflammatory back pain in the dorsal spine in TAK needs further scrutiny. PMID: 31969224 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
DiscussionAnkylosing spondylitis (also known as Bechterew disease and Marie Str ümpell disease). More common in males with 3:1 ratio.Spondyloarthritis is a group of diseases with common clinical, laboratory, and genetic features&association with human leukocyte antigen HLA-B27. Ankylosing spondylitis is the prototypic disease in the spectrum of spondyloarthritis which usually has axial skeletal manifestations. Other representative disorders in this spectrum of disease which usually have peripheral articular involvement, but axial skeleton manifestations are also frequently seen are --psori...
Source: Sumer's Radiology Site - Category: Radiology Authors: Source Type: blogs
Publication date: Available online 19 May 2018 Source:Joint Bone Spine Author(s): Clément Prati, Céline Demougeot, Xavier Guillot, Maxime Sondag, Frank Verhoeven, Daniel Wendling Ankylosing spondylitis (AS) is a chronic inflammatory joint disease that involves the entheses, causing inflammatory pain and functional impairments. Patients may experience extraarticular manifestations such as uveitis, psoriasis, and inflammatory bowel disease. These, together with the increased risk of cardiovascular disease and osteoporosis and the development of spinal fusion, are the main determinants of adverse disease outcom...
Source: Joint Bone Spine - Category: Orthopaedics Source Type: research
We present these common and distinct imaging manifestations that may potentially help distinguish between the entities in the diagnostic work-up. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Seminars in Musculoskeletal Radiology - Category: Radiology Authors: Tags: Review Article Source Type: research
Authors: Terenzi R, Monti S, Tesei G, Carli L Abstract The term spondyloarthritis (SpA) represents a condition characterised by a broad spectrum of clinical manifestations, laboratory abnormalities and imaging features; in particular, SpA is an inflammatory condition in which both peripheral and axial joints might be affected. The majority of people with this disease have either psoriatic arthritis or axial spondyloarthritis, which includes ankylosing spondylitis. Less common subgroups are enteropathic SpA, which is associated with inflammatory bowel diseases (Crohn's disease and ulcerative colitis), reactive arth...
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
Ankylosing spondylitis (AS), axial spondyloarthritis (SpA) and inflammatory back pain are common in inflammatory bowel disease (IBD) patients two decades after IBD diagnosis, according to findings from the IBSEN study.Reuters Health Information
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Gastroenterology News Source Type: news
Conclusion: There is a three‐fold higher prevalence of sacroiliitis in IBD compared with controls. Despite a growing awareness of this increased prevalence, many patients are not referred to a rheumatologist. This article is protected by copyright. All rights reserved.
Source: Arthritis Care and Research - Category: Rheumatology Authors: Tags: Brief Report Source Type: research
ConclusionA substantial proportion of seemingly healthy first‐degree relatives of HLA–B27–positive AS patients have clinical and/or imaging abnormalities suggestive of SpA. Thirty‐three percent could be classified as having SpA. Further follow‐up will show which first‐degree relatives will develop clinically manifest SpA.
Source: Arthritis and Rheumatism - Category: Rheumatology Authors: Tags: Spondyloarthritis Source Type: research
Abstract Ankylosing spondylitis (AS) and related forms of spondyloarthritis (SpA) are associated with some extra-articular features, and the most common symptomatic association is with acute anterior uveitis (AAU). Thus, approximately 40 % of patients with AS will experience a sudden onset of a unilateral anterior uveitis sometime during the course of their disease. Patients with AAU, especially those who are HLA-B27 positive, should be questioned about inflammatory low back pain and also evaluated for other clinical features of SpA. Since a prolonged delay in diagnosis is common among SpA patients and occur...
Source: Current Rheumatology Reports - Category: Rheumatology Source Type: research
CONCLUSIONS: High to moderate quality evidence indicates that both traditional and COX-2 NSAIDs are efficacious for treating axSpA, and moderate to low quality evidence indicates harms may not differ from placebo in the short term. Various NSAIDs are equally effective. Continuous NSAID use may reduce radiographic spinal progression, but this requires confirmation. PMID: 26186173 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - Category: Journals (General) Authors: Tags: Cochrane Database Syst Rev Source Type: research
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