Ulipristal Acetate vs Gonadotropin-Releasing Hormone Agonists Prior to Laparoscopic Myomectomy (MYOMEX Trial): Short-term Results of a Double-blind Randomized Controlled Trial

(Abstracted from Acta Obstet Gynecol Scand 2019; doi: 10.1111/aogs.13713) Two agents used for pretreatment of fibroids before myomectomy are gonadotropin-releasing hormone agonists (GnRHa)—considered a criterion standard—and ulipristal acetate (UPA), a selective progesterone receptor modulator (SPRM) recently approved for preoperative treatment. No randomized trials have compared pretreatment of uterine fibroids with GnRHa or UPA prior to laparoscopic myomectomy.
Source: Obstetrical and Gynecological Survey - Category: OBGYN Tags: GYNECOLOGY: OPERATIVE GYNECOLOGY Source Type: research