Medical doctors STUNNED as bone marrow transplant for leukemia treatment changes man’s DNA, proving medical interventions can OVERWRITE your genetic code
(Natural News) A Nevada man was shocked to learn that a bone marrow transplant he received actually changed his DNA and replaced it with that of his German donor. Chris Long of Reno is currently in remission from acute myeloid leukemia. Three months after his bone marrow transplant operation, he discovered that the DNA in...
Bone Marrow Transplantation, Published online: 06 March 2020; doi:10.1038/s41409-020-0835-3Correction: Redefining and measuring transplant conditioning intensity in current era: a study in acute myeloid leukemia patients
Bone Marrow Transplantation, Published online: 29 January 2020; doi:10.1038/s41409-020-0803-yRedefining and measuring transplant conditioning intensity in current era: a study in acute myeloid leukemia patients
Bone Marrow Transplantation, Published online: 28 January 2020; doi:10.1038/s41409-020-0799-3Total body irradiation (18 Gy) without chemotherapy as conditioning for allogeneic hematopoietic cell transplantation in refractory acute myeloid leukemia
Bone Marrow Transplantation, Published online: 03 December 2019; doi:10.1038/s41409-019-0762-3Excellent outcome after consolidation with autologous transplantation in patients with core binding factor acute myeloid leukemia
Bone Marrow Transplantation, Published online: 29 November 2019; doi:10.1038/s41409-019-0761-4HLA-mismatched microtransplantation for relapsed or refractory acute myeloid leukemia as a bridge to allogeneic hematopoietic stem cell transplantation
Bone Marrow Transplantation, Published online: 04 November 2019; doi:10.1038/s41409-019-0739-2Early achievement of measurable residual disease (MRD)-negative complete remission as predictor of outcome after myeloablative allogeneic hematopoietic cell transplantation in acute myeloid leukemia
A retrospective review of the medical reports of a patient who was undergoing treatment for graft versus host disease following bone marrow transplant for acute myeloid leukemia was conducted. The patient presented with persistent ocular irritation and injection. For an unclear period of time, he developed proptosis and binocular diplopia with limitation of extraocular motility insidiously. MRI revealed gross enlargement of extraocular muscles and bone marrow aspiration trephine confirmed relapse of leukemia. He then underwent chemotherapy with marked improvement of proptosis and extraocular motility. This case report high...
The era of next-generation sequencing (NGS) has led to a deeper understanding of the genetic complexity and heterogeneity of this disease, in addition to revealing mechanisms of disease relapse. Clinical NGS is becoming routine in clinical practice in both solid organ and hematologic malignancies to identify molecular markers of disease that might assist with diagnosis, prognosis, and the treatment of cancer. These tumor-specific markers also enable treatment response monitoring, as they serve as clonal markers unique to the disease. Continuous molecular monitoring also allows identification of disease recurrence with pote...
Bone Marrow Transplantation, Published online: 29 October 2019; doi:10.1038/s41409-019-0722-yInfluence of alternative donor type on early survival after hematopoietic stem cell transplantation for acute myeloid leukemia lacking a sibling donor
Bone Marrow Transplantation, Published online: 23 October 2019; doi:10.1038/s41409-019-0720-0Fludarabine/busulfan versus fludarabine/total-body-irradiation (2 Gy) as conditioning prior to allogeneic stem cell transplantation in patients (≥60 years) with acute myelogenous leukemia: a study of the acute leukemia working party of the EBMT