Ubiquitin ligases HUWE1 and NEDD4 cooperatively control signal-dependent PRC2-Ezh1 α/β-mediated adaptive stress response pathway in skeletal muscle cells

While the role of Polycomb group protein-mediated “cell memory” is well established in developmental contexts, little is known about their role in adult tissues and in particular in post-mitotic cells. Emergin...

Source: Epigenetics and Chromatin - December 19, 2019 Category: Genetics & Stem Cells Authors: Peng Liu, Muhammad Shuaib, Huoming Zhang, Seba Nadeef and Valerio Orlando Tags: Research Source Type: research