Correlation Between the Movement Disorder Society ’s Unified Parkinson’s Disease Rating Scale and Nonmotor Scales in Patients with Parkinson’s Disease

by Erika D. Driver-Dunckley, MD; Nan Zhang, MS; Holly A. Shill, MD; Shyamal H. Mehta, MD, PhD; Christine M. Belden, PsyD; Edward Y. Zamrini, MD; Kathryn Davis; Thomas G. Beach, MD, PhD; and Charles H. Adler, MD, PhD Drs. Driver-Dunckley, Mehta, and Adler are with the Department of Neurology of the Parkinson’s Disease and Movement […] The post Correlation Between the Movement Disorder Society’s Unified Parkinson’s Disease Rating Scale and Nonmotor Scales in Patients with Parkinson’s Disease appeared first on Innovations in Clinical Neuroscience.
Source: Innovations in Clinical Neuroscience - Category: Neuroscience Authors: Tags: Current Issue Neurology Original Research Parkinson's disease ESS MDS-UPDRS MSQ NPI-Q parkinson’s disease SCOPA-AUT Source Type: research

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The authors regret not having included the name of Camilla Zamfolini Hallal as a co-author of the referred article at the appropriate time. However, in view of the important contributions of the co-author to the article, we request this misunderstanding to...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
Condition:   Parkinson Disease Intervention:   Other: Cycling deep brain stimulation Sponsor:   University of Sao Paulo General Hospital Not yet recruiting
Source: - Category: Research Source Type: clinical trials
Patients with Parkinson's disease and diabetes treated with metformin experience better motor and nonmotor function than those not receiving the antihyperglycemic agent, pilot data suggest.Medscape Medical News
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Old bones creaking and aching from the kneeling. Hands warped with the weave and weft of life that don’t quite meet as they once did. And looking back the prayers and wishes she had made over many years had not yet come to pass. But still she turns up, every day, as the bell tolled and the doors opened. Making her way carefully to the back pew she slides along to the usual spot and kneels in supplication. Slowly she forms an image in her mind of a child holding the hand of his father. She scrolls forward through the years that have since passed, gently imagining how he changes over time. By the time she finishes he i...
Source: The Hysterectomy Association - Category: OBGYN Authors: Tags: Writing friday fiction Source Type: news
Contributor : Chung-Yang KaoSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusElevated COUP-TFII levels are found in Parkinson ’s disease. COUP-TFII overexpression in mouse dopaminergic neurons caused neurodegeneration. The goal of this study is to identify molecular mechanisms of COUP-TFII-mediated cell death through RNAseq.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
Contributors : Maarit I Tiirikainen ; Rodney C Go ; Michael J Corley ; G W Ross ; Helen Petrovitch ; Kamal H Masaki ; Alika K Maunakea ; Qimei HeSeries Type : Methylation profiling by arrayOrganism : Homo sapiensParkinson ’s Disease (PD) is a disease of the central nervous system that progressively affects the motor system. Epidemiological studies have provided evidence that exposure to agriculture-related occupations or agrichemicals elevate a person’s risk for PD. Here, we sought to examine the possible epigen etic changes associated with working on a plantation on Oahu, HI and/or exposure to organochlorines ...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Methylation profiling by array Homo sapiens Source Type: research
Authors: Raval U, Harary J, Zeng E, Pasinetti GM Abstract INTRODUCTION: Age related neurodegenerative disorders affect millions of people around the world. The role of the gut microbiome (GM) in neurodegenerative disorders has been elucidated over the past few years. Dysbiosis of the gut microbiome ultimately results in neurodegeneration. However, the gut microbiome can be modulated to promote neuro-resilience. AREAS COVERED: This review is focused on demonstrating the role of the gut microbiome in host physiology in Parkinson's disease (PD) and other neurodegenerative disorders. We will discuss how the microbiome ...
Source: Expert Review of Neurotherapeutics - Category: Neurology Tags: Expert Rev Neurother Source Type: research
Source: International Journal of Speech-Language Pathology - Category: Speech-Language Pathology Authors: Source Type: research
This minireview discusses our current understanding of the olfactory dysfunction that is frequently observed in sporadic and familial forms of Parkinson's disease and parkinsonian syndromes. We review the salient characteristics of olfactory dysfunction in these conditions, discussing its prevalence and characteristics, how neuronal processes and circuits are altered in Parkinson's disease, and what is assessed by clinically used measures of olfactory function. We highlight how studies of monogenic Parkinson's disease and investigations in ethnically diverse populations have contributed to understanding the mechanisms unde...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
The objective of this study was to characterize the firing behavior of single motor units in the elbow flexor and extensor muscles during isometric contractions in people with mild-to-moderate PD. Ten individuals with PD (off-medication) and nine healthy controls were tested. Motor unit spike times were recorded via intramuscular EMG from the biceps and triceps brachii muscles during 30-s isometric contractions at 10% maximum voluntary elbow flexion and elbow extension torque, respectively. We selected variables of mean motor unit discharge rate, discharge variability, and torque variability to evaluate motor abnormalities...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
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