Loss of amyloid precursor protein exacerbates early inflammation in Niemann-Pick disease type C

Niemann-Pick disease type C (NPC) is a progressive neurodegenerative condition that results in early fatality. NPC is inherited in an autosomal recessive pattern from mutations in NPC1 or NPC2 genes. The etiology...

Source: Journal of Neuroinflammation - December 17, 2019 Category: Neurology Authors: Samuel D. Shin, Alexandra Shin, Karina Mayagoitia, Lorraine Siebold, Marsilio Rubini, Christopher G. Wilson, Denise L. Bellinger and Salvador Soriano Tags: Research Source Type: research