Anti-malarial ozonides OZ439 and OZ609 tested at clinically relevant compound exposure parameters in a novel ring-stage survival assay

Drug efficacy against kelch 13 mutant malaria parasites can be determined in vitro with the ring-stage survival assay (RSA). The conventional assay protocol reflects the exposure profile of dihydroartemisinin.

Source: Malaria Journal - December 18, 2019 Category: Infectious Diseases Authors: Annabelle Walz, Didier Leroy, Nicole Andenmatten, Pascal M äser and Sergio Wittlin Tags: Research Source Type: research